Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 51278
MIM: 607177
HGNC: 5393
Ensembl: ENSG00000162783
Variants:
dbSNP: 51278
ClinVar: 51278
TCGA: ENSG00000162783
COSMIC: IER5
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000162783 | ENST00000367577 | Q5VY09 |
Expression (GTEx)
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 36047562 | 2023 | PP2A-B55 and its adapter proteins IER2 and IER5 regulate the activity of RB family proteins and the expression of cell cycle-related genes. | 4 |
| 36047562 | 2023 | PP2A-B55 and its adapter proteins IER2 and IER5 regulate the activity of RB family proteins and the expression of cell cycle-related genes. | 4 |
| 31669744 | 2020 | Nuclear import of IER5 is mediated by a classical bipartite nuclear localization signal and is required for HSF1 full activation. | 7 |
| 32471508 | 2020 | Novel role of PAF1 in attenuating radiosensitivity in cervical cancer by inhibiting IER5 transcription. | 6 |
| 32936072 | 2020 | IER5, a DNA damage response gene, is required for Notch-mediated induction of squamous cell differentiation. | 11 |
| 31669744 | 2020 | Nuclear import of IER5 is mediated by a classical bipartite nuclear localization signal and is required for HSF1 full activation. | 7 |
| 32471508 | 2020 | Novel role of PAF1 in attenuating radiosensitivity in cervical cancer by inhibiting IER5 transcription. | 6 |
| 32936072 | 2020 | IER5, a DNA damage response gene, is required for Notch-mediated induction of squamous cell differentiation. | 11 |
| 30599213 | 2019 | IER family proteins are regulators of protein phosphatase PP2A and modulate the phosphorylation status of CDC25A. | 6 |
| 30599213 | 2019 | IER family proteins are regulators of protein phosphatase PP2A and modulate the phosphorylation status of CDC25A. | 6 |
| 28430589 | 2017 | IER5 as a promising predictive marker promotes irradiation-induced apoptosis in cervical cancer tissues from patients undergoing chemoradiotherapy. | 5 |
| 29104487 | 2017 | IER5 is involved in DNA Double-Strand Breaks Repair in Association with PAPR1 in Hela Cells. | 8 |
| 28430589 | 2017 | IER5 as a promising predictive marker promotes irradiation-induced apoptosis in cervical cancer tissues from patients undergoing chemoradiotherapy. | 5 |
| 29104487 | 2017 | IER5 is involved in DNA Double-Strand Breaks Repair in Association with PAPR1 in Hela Cells. | 8 |
| 26754925 | 2016 | IER5 generates a novel hypo-phosphorylated active form of HSF1 and contributes to tumorigenesis. | 29 |
Citation
Dessen P
IER5 (immediate early response 5)
Atlas Genet Cytogenet Oncol Haematol. 2007-04-01
Online version: http://atlasgeneticsoncology.org/gene/46759/ier5
