Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 116835
MIM: 610702
HGNC: 16193
Ensembl: ENSG00000132622
Variants:
dbSNP: 116835
ClinVar: 116835
TCGA: ENSG00000132622
COSMIC: HSPA12B
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000132622 | ENST00000254963 | Q96MM6 |
| ENSG00000132622 | ENST00000399701 | Q5JX83 |
Expression (GTEx)
Pathways
| Pathway | Source | External ID |
|---|---|---|
| Cellular responses to stress | REACTOME | R-HSA-2262752 |
| Cellular response to heat stress | REACTOME | R-HSA-3371556 |
| Regulation of HSF1-mediated heat shock response | REACTOME | R-HSA-3371453 |
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 32457753 | 2020 | Novel Role of Endothelial Derived Exosomal HSPA12B in Regulating Macrophage Inflammatory Responses in Polymicrobial Sepsis. | 21 |
| 32457753 | 2020 | Novel Role of Endothelial Derived Exosomal HSPA12B in Regulating Macrophage Inflammatory Responses in Polymicrobial Sepsis. | 21 |
| 29115487 | 2018 | MiR-4505 aggravates lipopolysaccharide-induced vascular endothelial injury by targeting heat shock protein A12B. | 8 |
| 29115487 | 2018 | MiR-4505 aggravates lipopolysaccharide-induced vascular endothelial injury by targeting heat shock protein A12B. | 8 |
| 27083952 | 2016 | Heat shock protein A12B protects against sepsis-induced impairment in vascular endothelial permeability. | 15 |
| 27644317 | 2016 | HSPA12B Attenuated Acute Myocardial Ischemia/reperfusion Injury via Maintaining Endothelial Integrity in a PI3K/Akt/mTOR-dependent Mechanism. | 28 |
| 27083952 | 2016 | Heat shock protein A12B protects against sepsis-induced impairment in vascular endothelial permeability. | 15 |
| 27644317 | 2016 | HSPA12B Attenuated Acute Myocardial Ischemia/reperfusion Injury via Maintaining Endothelial Integrity in a PI3K/Akt/mTOR-dependent Mechanism. | 28 |
| 25545050 | 2015 | HSPA12B inhibits lipopolysaccharide-induced inflammatory response in human umbilical vein endothelial cells. | 16 |
| 25909170 | 2015 | HSPA12B: a novel facilitator of lung tumor growth. | 11 |
| 26428665 | 2015 | HSPA12B regulates SSeCKS-mediated astrocyte inflammatory activation in neuroinflammation. | 3 |
| 25545050 | 2015 | HSPA12B inhibits lipopolysaccharide-induced inflammatory response in human umbilical vein endothelial cells. | 16 |
| 25909170 | 2015 | HSPA12B: a novel facilitator of lung tumor growth. | 11 |
| 26428665 | 2015 | HSPA12B regulates SSeCKS-mediated astrocyte inflammatory activation in neuroinflammation. | 3 |
| 24977412 | 2014 | Plasma HSPA12B is a potential predictor for poor outcome in severe sepsis. | 6 |
Citation
Dessen P
HSPA12B (heat shock protein family A (Hsp70) member 12B)
Atlas Genet Cytogenet Oncol Haematol. 2007-04-01
Online version: http://atlasgeneticsoncology.org/gene/46775/hspa12b
