FBXO38 (F-box protein 38)

2007-04-01  

Identity

HGNC
FBXO38
LOCATION
5q32
LOCUSID
81545
ALIAS
Fbx38,HMN2D,MOKA,SP329
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 81545
MIM: 608533
HGNC: 28844
Ensembl: ENSG00000145868

Variants:

dbSNP: 81545
ClinVar: 81545
TCGA: ENSG00000145868
COSMIC: FBXO38

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000145868ENST00000296701Q6PIJ6
ENSG00000145868ENST00000340253Q6PIJ6
ENSG00000145868ENST00000394370Q6PIJ6
ENSG00000145868ENST00000513826Q6PIJ6

Expression (GTEx)

0
5
10
15
20
25
30
35
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
382778172024FBXO38 deficiency promotes lysosome-dependent STING degradation and inhibits cGAS-STING pathway activation.1
388231192024Identification of rare variants in the FBXO38 gene of patients with chronic inflammatory demyelinating polyradiculoneuropathy.0
382778172024FBXO38 deficiency promotes lysosome-dependent STING degradation and inhibits cGAS-STING pathway activation.1
388231192024Identification of rare variants in the FBXO38 gene of patients with chronic inflammatory demyelinating polyradiculoneuropathy.0
378216212023FBXO38 regulates macrophage polarization to control the development of cancer and colitis.2
378216212023FBXO38 regulates macrophage polarization to control the development of cancer and colitis.2
308043942019USP7 Regulates Cytokinesis through FBXO38 and KIF20B.18
312690662019Analysis of genetically driven alternative splicing identifies FBXO38 as a novel COPD susceptibility gene.15
308043942019USP7 Regulates Cytokinesis through FBXO38 and KIF20B.18
312690662019Analysis of genetically driven alternative splicing identifies FBXO38 as a novel COPD susceptibility gene.15
304876062018FBXO38 mediates PD-1 ubiquitination and regulates anti-tumour immunity of T cells.121
304876062018FBXO38 mediates PD-1 ubiquitination and regulates anti-tumour immunity of T cells.121
266436022015Two-stage comprehensive evaluation of genetic susceptibility of common variants in FBXO38, AP3B2 and WHAMM to severe chronic periodontitis.8
266436022015Two-stage comprehensive evaluation of genetic susceptibility of common variants in FBXO38, AP3B2 and WHAMM to severe chronic periodontitis.8
205495152010Genome-wide searching of rare genetic variants in WTCCC data.31

Citation

Dessen P

FBXO38 (F-box protein 38)

Atlas Genet Cytogenet Oncol Haematol. 2007-04-01

Online version: http://atlasgeneticsoncology.org/gene/46778/fbxo38