ADAMTS14 (ADAM metallopeptidase with thrombospondin type 1 motif 14)

2007-04-01  

Identity

HGNC
LOCATION
10q22.1
LOCUSID
ALIAS
-
FUSION GENES

Other Information

Locus ID:

NCBI: 140766
MIM: 607506
HGNC: 14899
Ensembl: ENSG00000138316

Variants:

dbSNP: 140766
ClinVar: 140766
TCGA: ENSG00000138316
COSMIC: ADAMTS14

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000138316ENST00000373207Q8WXS8
ENSG00000138316ENST00000373208Q8WXS8

Expression (GTEx)

0
5
10
15

Pathways

PathwaySourceExternal ID
Metabolism of proteinsREACTOMER-HSA-392499
Post-translational protein modificationREACTOMER-HSA-597592
O-linked glycosylationREACTOMER-HSA-5173105
O-glycosylation of TSR domain-containing proteinsREACTOMER-HSA-5173214
DiseaseREACTOMER-HSA-1643685
Diseases of glycosylationREACTOMER-HSA-3781865
Extracellular matrix organizationREACTOMER-HSA-1474244
Collagen formationREACTOMER-HSA-1474290
Collagen biosynthesis and modifying enzymesREACTOMER-HSA-1650814
Diseases associated with O-glycosylation of proteinsREACTOMER-HSA-3906995
Defective B3GALTL causes Peters-plus syndrome (PpS)REACTOMER-HSA-5083635

References

Pubmed IDYearTitleCitations
379296352024Opposing roles for ADAMTS2 and ADAMTS14 in myofibroblast differentiation and function.1
379296352024Opposing roles for ADAMTS2 and ADAMTS14 in myofibroblast differentiation and function.1
366581132023Large scale phenotype imputation and in vivo functional validation implicate ADAMTS14 as an adiposity gene.1
375506752023Correlation investigation between a single nucleotide polymorphism in ADAMTS14 (rs4747096) and osteoarthritis: a meta-analysis.0
377253022023Association between ADAMTS14_rs4747096 gene polymorphism and bone mineral density of Chinese Han population residing in fluorine exposed areas in ShanXi Province, China.1
366581132023Large scale phenotype imputation and in vivo functional validation implicate ADAMTS14 as an adiposity gene.1
375506752023Correlation investigation between a single nucleotide polymorphism in ADAMTS14 (rs4747096) and osteoarthritis: a meta-analysis.0
377253022023Association between ADAMTS14_rs4747096 gene polymorphism and bone mineral density of Chinese Han population residing in fluorine exposed areas in ShanXi Province, China.1
348561622022The expression of ADAMTS14 is regulated by promoter DNA methylation and is associated with poor prognosis in colorectal cancer.2
355725052022Survival Prognosis, Tumor Immune Landscape, and Immune Responses of ADAMTS14 in Clear Cell Renal Cell Carcinoma and Its Potential Mechanisms.8
348561622022The expression of ADAMTS14 is regulated by promoter DNA methylation and is associated with poor prognosis in colorectal cancer.2
355725052022Survival Prognosis, Tumor Immune Landscape, and Immune Responses of ADAMTS14 in Clear Cell Renal Cell Carcinoma and Its Potential Mechanisms.8
333000672021Inflammasome components and ADAMTS4 in premature rupture of membranes.8
339321422021Identification of crucial noncoding RNAs and mRNAs in hypertrophic scars via RNA sequencing.5
341458042021Lack of association between MMP13 (rs3819089), ADAM12 (rs3740199-rs1871054) and ADAMTS14 (rs4747096) genotypes and advanced-stage knee osteoarthritis.5

Citation

Dessen P

ADAMTS14 (ADAM metallopeptidase with thrombospondin type 1 motif 14)

Atlas Genet Cytogenet Oncol Haematol. 2007-04-01

Online version: http://atlasgeneticsoncology.org/gene/46785/adamts14