RNF121 (ring finger protein 121)

2007-04-01  

Identity

HGNC
RNF121
LOCATION
11q13.4
LOCUSID
55298
ALIAS
-
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 55298
HGNC: 21070
Ensembl: ENSG00000137522

Variants:

dbSNP: 55298
ClinVar: 55298
TCGA: ENSG00000137522
COSMIC: RNF121

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000137522ENST00000361756Q9H920
ENSG00000137522ENST00000393711F8WDV7
ENSG00000137522ENST00000393713C9JQY5
ENSG00000137522ENST00000525243H0YEH6
ENSG00000137522ENST00000526549E9PRV6
ENSG00000137522ENST00000530058E9PLR7
ENSG00000137522ENST00000530137G3V148
ENSG00000137522ENST00000530655E9PN80
ENSG00000137522ENST00000533380E9PKE9

Expression (GTEx)

0
5
10
15
20
25
30
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
299551332018Integrative analysis of oncogenic fusion genes and their functional impact in colorectal cancer.21
301490632018Really interesting new gene finger protein 121 is a tumor suppressor of renal cell carcinoma.1
299551332018Integrative analysis of oncogenic fusion genes and their functional impact in colorectal cancer.21
301490632018Really interesting new gene finger protein 121 is a tumor suppressor of renal cell carcinoma.1
266028612016RNF121 Inhibits Angiogenic Growth Factor Signaling by Restricting Cell Surface Expression of VEGFR-2.13
266028612016RNF121 Inhibits Angiogenic Growth Factor Signaling by Restricting Cell Surface Expression of VEGFR-2.13
249286852014Really interesting new gene finger protein 121 is a novel Golgi-localized membrane protein that regulates apoptosis.3
253885462014The E3 ubiquitin ligase RNF121 is a positive regulator of NF-κB activation.11
249286852014Really interesting new gene finger protein 121 is a novel Golgi-localized membrane protein that regulates apoptosis.3
253885462014The E3 ubiquitin ligase RNF121 is a positive regulator of NF-κB activation.11

Citation

Dessen P

RNF121 (ring finger protein 121)

Atlas Genet Cytogenet Oncol Haematol. 2007-04-01

Online version: http://atlasgeneticsoncology.org/gene/46850/case-report-explorer/deep-insight-explorer/favicon/manifest.json