Identity
HGNC
LOCATION
1p36.22
LOCUSID
ALIAS
FBG2,FBS2,FBX6,Fbx6b
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 26270
MIM: 605647
HGNC: 13585
Ensembl: ENSG00000116663
Variants:
dbSNP: 26270
ClinVar: 26270
TCGA: ENSG00000116663
COSMIC: FBXO6
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000116663 | ENST00000376753 | Q9NRD1 |
| ENSG00000116663 | ENST00000449067 | J3KQ72 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 35063764 | 2022 | The USP18-FBXO6 axis maintains the malignancy of ovarian cancer. | 1 |
| 35063764 | 2022 | The USP18-FBXO6 axis maintains the malignancy of ovarian cancer. | 1 |
| 33767133 | 2021 | FBXO6-mediated RNASET2 ubiquitination and degradation governs the development of ovarian cancer. | 14 |
| 33767133 | 2021 | FBXO6-mediated RNASET2 ubiquitination and degradation governs the development of ovarian cancer. | 14 |
| 31140586 | 2019 | Fbxo6 confers drug-sensitization to cisplatin via inhibiting the activation of Chk1 in non-small cell lung cancer. | 12 |
| 31308089 | 2019 | Noncanonical Role of FBXO6 in Regulating Antiviral Immunity. | 10 |
| 31140586 | 2019 | Fbxo6 confers drug-sensitization to cisplatin via inhibiting the activation of Chk1 in non-small cell lung cancer. | 12 |
| 31308089 | 2019 | Noncanonical Role of FBXO6 in Regulating Antiviral Immunity. | 10 |
| 30526252 | 2018 | Overexpression of Fbxo6 inactivates spindle checkpoint by interacting with Mad2 and BubR1. | 5 |
| 30526252 | 2018 | Overexpression of Fbxo6 inactivates spindle checkpoint by interacting with Mad2 and BubR1. | 5 |
| 27855403 | 2016 | FBXO6-Mediated Ubiquitination and Degradation of Ero1L Inhibits Endoplasmic Reticulum Stress-Induced Apoptosis. | 19 |
| 27855403 | 2016 | FBXO6-Mediated Ubiquitination and Degradation of Ero1L Inhibits Endoplasmic Reticulum Stress-Induced Apoptosis. | 19 |
| 25374377 | 2014 | FBXO6 attenuates cadmium toxicity in HEK293 cells by inhibiting ER stress and JNK activation. | 8 |
| 25374377 | 2014 | FBXO6 attenuates cadmium toxicity in HEK293 cells by inhibiting ER stress and JNK activation. | 8 |
| 22268729 | 2012 | Proteomic identification of common SCF ubiquitin ligase FBXO6-interacting glycoproteins in three kinds of cells. | 18 |
Citation
Dessen P
FBXO6 (F-box protein 6)
Atlas Genet Cytogenet Oncol Haematol. 2007-04-01
Online version: http://atlasgeneticsoncology.org/gene/46885/fbxo6
