PPM1G (protein phosphatase, Mg2+/Mn2+ dependent 1G)

2007-04-01  

Identity

HGNC
PPM1G
LOCATION
2p23.3
LOCUSID
5496
ALIAS
PP2CG,PP2CGAMMA,PPP2CG
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 5496
MIM: 605119
HGNC: 9278
Ensembl: ENSG00000115241

Variants:

dbSNP: 5496
ClinVar: 5496
TCGA: ENSG00000115241
COSMIC: PPM1G

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000115241ENST00000344034O15355
ENSG00000115241ENST00000344034Q6IAU5

Expression (GTEx)

0
100
200
300
400
500
600
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
363499382023PPM1G promotes the progression of lung adenocarcinoma by inhibiting p38 activation via dephosphorylation of MEK6.1
373874072023Prognostic and immunological potential of PPM1G in lung adenocarcinoma.1
363499382023PPM1G promotes the progression of lung adenocarcinoma by inhibiting p38 activation via dephosphorylation of MEK6.1
373874072023Prognostic and immunological potential of PPM1G in lung adenocarcinoma.1
343663222022High expression of PPM1G is associated with the progression and poor prognosis of hepatocellular carcinoma.4
343663222022High expression of PPM1G is associated with the progression and poor prognosis of hepatocellular carcinoma.4
339527162021Prognostic and immunological potential of PPM1G in hepatocellular carcinoma.7
342902392021PPM1G promotes the progression of hepatocellular carcinoma via phosphorylation regulation of alternative splicing protein SRSF3.24
339527162021Prognostic and immunological potential of PPM1G in hepatocellular carcinoma.7
342902392021PPM1G promotes the progression of hepatocellular carcinoma via phosphorylation regulation of alternative splicing protein SRSF3.24
322185002020Association of PPM1G methylation with risk-taking in alcohol use disorder.1
329193042020Proteomics reveals protein phosphatase 1γ as a biomarker associated with Hippo signal pathway in glioma.5
332887252020The ARF tumor suppressor targets PPM1G/PP2Cγ to counteract NF-κB transcription tuning cell survival and the inflammatory response.8
322185002020Association of PPM1G methylation with risk-taking in alcohol use disorder.1
329193042020Proteomics reveals protein phosphatase 1γ as a biomarker associated with Hippo signal pathway in glioma.5

Citation

Dessen P

PPM1G (protein phosphatase, Mg2+/Mn2+ dependent 1G)

Atlas Genet Cytogenet Oncol Haematol. 2007-04-01

Online version: http://atlasgeneticsoncology.org/gene/46927