Identity
HGNC
LOCATION
10q22.1
LOCUSID
ALIAS
GUA,GURDB,RH-II/GU,RH-II/GuA
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 9188
MIM: 606357
HGNC: 2744
Ensembl: ENSG00000165732
Variants:
dbSNP: 9188
ClinVar: 9188
TCGA: ENSG00000165732
COSMIC: DDX21
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000165732 | ENST00000354185 | Q9NR30 |
| ENSG00000165732 | ENST00000620315 | Q9NR30 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38387756 | 2024 | Lnc-PLCB1 is stabilized by METTL14 induced m6A modification and inhibits Helicobacter pylori mediated gastric cancer by destabilizing DDX21. | 1 |
| 38572589 | 2024 | m(6)A-dependent upregulation of DDX21 by super-enhancer-driven IGF2BP2 and IGF2BP3 facilitates progression of acute myeloid leukaemia. | 1 |
| 38387756 | 2024 | Lnc-PLCB1 is stabilized by METTL14 induced m6A modification and inhibits Helicobacter pylori mediated gastric cancer by destabilizing DDX21. | 1 |
| 38572589 | 2024 | m(6)A-dependent upregulation of DDX21 by super-enhancer-driven IGF2BP2 and IGF2BP3 facilitates progression of acute myeloid leukaemia. | 1 |
| 36608661 | 2023 | Glucose dissociates DDX21 dimers to regulate mRNA splicing and tissue differentiation. | 6 |
| 37029300 | 2023 | Phase separation of DDX21 promotes colorectal cancer metastasis via MCM5-dependent EMT pathway. | 10 |
| 37072811 | 2023 | LINC00240 in the 6p22.1 risk locus promotes gastric cancer progression through USP10-mediated DDX21 stabilization. | 4 |
| 37904456 | 2023 | RRP9 and DDX21 as new biomarkers of colorectal cancer. | 0 |
| 37988222 | 2023 | Joint effect of RRP9 and DDX21 on development of colorectal cancer and keloid. | 0 |
| 36608661 | 2023 | Glucose dissociates DDX21 dimers to regulate mRNA splicing and tissue differentiation. | 6 |
| 37029300 | 2023 | Phase separation of DDX21 promotes colorectal cancer metastasis via MCM5-dependent EMT pathway. | 10 |
| 37072811 | 2023 | LINC00240 in the 6p22.1 risk locus promotes gastric cancer progression through USP10-mediated DDX21 stabilization. | 4 |
| 37904456 | 2023 | RRP9 and DDX21 as new biomarkers of colorectal cancer. | 0 |
| 37988222 | 2023 | Joint effect of RRP9 and DDX21 on development of colorectal cancer and keloid. | 0 |
| 34987058 | 2022 | The Roles of RNA Helicases in DNA Damage Repair and Tumorigenesis Reveal Precision Therapeutic Strategies. | 9 |
Citation
Dessen P
DDX21 (DExD-box helicase 21)
Atlas Genet Cytogenet Oncol Haematol. 2007-04-01
Online version: http://atlasgeneticsoncology.org/gene/46952/ddx21
