GPSM2 (G protein signaling modulator 2)

2007-04-01  

Identity

HGNC
LOCATION
1p13.3
LOCUSID
ALIAS
CMCS,DFNB82,LGN,PINS
FUSION GENES

Other Information

Locus ID:

NCBI: 29899
MIM: 609245
HGNC: 29501
Ensembl: ENSG00000121957

Variants:

dbSNP: 29899
ClinVar: 29899
TCGA: ENSG00000121957
COSMIC: GPSM2

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000121957ENST00000264126P81274
ENSG00000121957ENST00000264126A0A024R0F8
ENSG00000121957ENST00000406462P81274
ENSG00000121957ENST00000406462A0A024R0F8
ENSG00000121957ENST00000435475B0QZD0
ENSG00000121957ENST00000435987Q5T1N9
ENSG00000121957ENST00000441735H0Y4A4
ENSG00000121957ENST00000446797B0QZC9
ENSG00000121957ENST00000642355P81274
ENSG00000121957ENST00000642355A0A024R0F8
ENSG00000121957ENST00000643094A0A2R8Y673
ENSG00000121957ENST00000643643A0A2R8Y6E3
ENSG00000121957ENST00000645164A0A2R8Y896
ENSG00000121957ENST00000645255A0A2R8YCX1

Expression (GTEx)

0
5
10
15
20
25

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
386744082024G-Protein Signaling Modulator 2 as a Potential Biomarker in Colorectal Cancer: Integrative Analysis Using Genetic Profiling and Pan-Cancer Studies.0
386744082024G-Protein Signaling Modulator 2 as a Potential Biomarker in Colorectal Cancer: Integrative Analysis Using Genetic Profiling and Pan-Cancer Studies.0
359408212022Truncated isoforms of GPSM2 containing the GoLoco motif region promote CD4(+) T-cell migration in SLE.0
359408212022Truncated isoforms of GPSM2 containing the GoLoco motif region promote CD4(+) T-cell migration in SLE.0
320202112020Downregulation of GPSM2 is associated with primary resistance to paclitaxel in breast cancer.6
320580482020Loss of G-protein-signaling modulator 2 accelerates proliferation of lung adenocarcinoma via EGFR signaling pathway.11
328124932020GPSM2 Serves as an Independent Prognostic Biomarker for Liver Cancer Survival.4
320202112020Downregulation of GPSM2 is associated with primary resistance to paclitaxel in breast cancer.6
320580482020Loss of G-protein-signaling modulator 2 accelerates proliferation of lung adenocarcinoma via EGFR signaling pathway.11
328124932020GPSM2 Serves as an Independent Prognostic Biomarker for Liver Cancer Survival.4
311018172019Hexameric NuMA:LGN structures promote multivalent interactions required for planar epithelial divisions.18
317325602019Intramolecular interaction in LGN, an adaptor protein that regulates mitotic spindle orientation.8
311018172019Hexameric NuMA:LGN structures promote multivalent interactions required for planar epithelial divisions.18
317325602019Intramolecular interaction in LGN, an adaptor protein that regulates mitotic spindle orientation.8
295237892018Insc:LGN tetramers promote asymmetric divisions of mammary stem cells.18

Citation

Dessen P

GPSM2 (G protein signaling modulator 2)

Atlas Genet Cytogenet Oncol Haematol. 2007-04-01

Online version: http://atlasgeneticsoncology.org/gene/47143/gpsm2