PPP1R10 (protein phosphatase 1 regulatory subunit 10)

2007-04-01  

Identity

HGNC
PPP1R10
LOCATION
6p21.33
LOCUSID
5514
ALIAS
CAT53,FB19,PNUTS,PP1R10,R111,p99
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 5514
MIM: 603771
HGNC: 9284
Ensembl: ENSG00000204569

Variants:

dbSNP: 5514
ClinVar: 5514
TCGA: ENSG00000204569
COSMIC: PPP1R10

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000204569ENST00000376511Q96QC0
ENSG00000204569ENST00000376511Q2L6I0

Expression (GTEx)

0
10
20
30
40
50
60
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
351397132023Alternatively-spliced lncRNA-PNUTS promotes HCC cell EMT via regulating ZEB1 expression.3
351397132023Alternatively-spliced lncRNA-PNUTS promotes HCC cell EMT via regulating ZEB1 expression.3
323772722020Upregulation of Phosphatase 1 Nuclear-Targeting Subunit (PNUTS) Is an Independent Predictor of Poor Prognosis in Prostate Cancer.3
323772722020Upregulation of Phosphatase 1 Nuclear-Targeting Subunit (PNUTS) Is an Independent Predictor of Poor Prognosis in Prostate Cancer.3
301904382019Phosphatase 1 Nuclear Targeting Subunit (PNUTS) Regulates Aurora Kinases and Mitotic Progression.13
316779742019Control of RNA Pol II Speed by PNUTS-PP1 and Spt5 Dephosphorylation Facilitates Termination by a "Sitting Duck Torpedo" Mechanism.91
301904382019Phosphatase 1 Nuclear Targeting Subunit (PNUTS) Regulates Aurora Kinases and Mitotic Progression.13
316779742019Control of RNA Pol II Speed by PNUTS-PP1 and Spt5 Dephosphorylation Facilitates Termination by a "Sitting Duck Torpedo" Mechanism.91
297640052018Identification of Novel Functional Variants of SIN3A and SRSF1 among Somatic Variants in Acute Myeloid Leukemia Patients.3
301585172018MYC dephosphorylation by the PP1/PNUTS phosphatase complex regulates chromatin binding and protein stability.30
297640052018Identification of Novel Functional Variants of SIN3A and SRSF1 among Somatic Variants in Acute Myeloid Leukemia Patients.3
301585172018MYC dephosphorylation by the PP1/PNUTS phosphatase complex regulates chromatin binding and protein stability.30
288256982017A regulated PNUTS mRNA to lncRNA splice switch mediates EMT and tumour progression.161
288256982017A regulated PNUTS mRNA to lncRNA splice switch mediates EMT and tumour progression.161
275918552016Biophysical Analysis of the N-Terminal Domain from the Human Protein Phosphatase 1 Nuclear Targeting Subunit PNUTS Suggests an Extended Transcription Factor TFIIS-Like Fold.4

Citation

Dessen P

PPP1R10 (protein phosphatase 1 regulatory subunit 10)

Atlas Genet Cytogenet Oncol Haematol. 2007-04-01

Online version: http://atlasgeneticsoncology.org/gene/47145/gene-fusions/js/template.js