Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 286151
MIM: 609110
HGNC: 28521
Ensembl: ENSG00000156509
Variants:
dbSNP: 286151
ClinVar: 286151
TCGA: ENSG00000156509
COSMIC: FBXO43
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000156509 | ENST00000428847 | Q4G163 |
| ENSG00000156509 | ENST00000517806 | E5RHI5 |
Expression (GTEx)
Pathways
| Pathway | Source | External ID |
|---|---|---|
| Oocyte meiosis | KEGG | ko04114 |
| Oocyte meiosis | KEGG | hsa04114 |
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 36710413 | 2023 | Association between F-box-only protein 43 overexpression and hepatocellular carcinoma pathogenesis and prognosis. | 4 |
| 37250703 | 2023 | Clinical significance of FBXO43 in hepatocellular carcinoma and its impact on tumor cell proliferation, migration and invasion. | 2 |
| 36710413 | 2023 | Association between F-box-only protein 43 overexpression and hepatocellular carcinoma pathogenesis and prognosis. | 4 |
| 37250703 | 2023 | Clinical significance of FBXO43 in hepatocellular carcinoma and its impact on tumor cell proliferation, migration and invasion. | 2 |
| 34595750 | 2022 | A homozygous loss-of-function mutation in FBXO43 causes human non-obstructive azoospermia. | 3 |
| 34595750 | 2022 | A homozygous loss-of-function mutation in FBXO43 causes human non-obstructive azoospermia. | 3 |
| 34052850 | 2021 | FBXO43 variants in patients with female infertility characterized by early embryonic arrest. | 12 |
| 34645483 | 2021 | Downregulation of the FBXO43 gene inhibits tumor growth in human breast cancer by limiting its interaction with PCNA. | 7 |
| 34052850 | 2021 | FBXO43 variants in patients with female infertility characterized by early embryonic arrest. | 12 |
| 34645483 | 2021 | Downregulation of the FBXO43 gene inhibits tumor growth in human breast cancer by limiting its interaction with PCNA. | 7 |
| 32253818 | 2020 | EMI2 expression as a poor prognostic factor in patients with breast cancer. | 11 |
| 32253818 | 2020 | EMI2 expression as a poor prognostic factor in patients with breast cancer. | 11 |
| 30878252 | 2019 | A novel homozygous FBXO43 mutation associated with male infertility and teratozoospermia in a consanguineous Chinese family. | 11 |
| 30878252 | 2019 | A novel homozygous FBXO43 mutation associated with male infertility and teratozoospermia in a consanguineous Chinese family. | 11 |
| 18550795 | 2008 | Cdc2 and Mos regulate Emi2 stability to promote the meiosis I-meiosis II transition. | 15 |
Citation
Dessen P
FBXO43 (F-box protein 43)
Atlas Genet Cytogenet Oncol Haematol. 2007-04-01
Online version: http://atlasgeneticsoncology.org/gene/47237/fbxo43
