DPPA3 (developmental pluripotency associated 3)

2007-04-01  

Identity

HGNC
DPPA3
LOCATION
12p13.31
LOCUSID
359787
ALIAS
Pgc7,STELLA

Other Information

Locus ID:

NCBI: 359787
MIM: 608408
HGNC: 19199
Ensembl: ENSG00000187569

Variants:

dbSNP: 359787
ClinVar: 359787
TCGA: ENSG00000187569
COSMIC: DPPA3

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000187569ENST00000345088Q6W0C5

Expression (GTEx)

0
1
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

References

Pubmed IDYearTitleCitations
388981242024Structure of human DPPA3 bound to the UHRF1 PHD finger reveals its functional and structural differences from mouse DPPA3.0
388981242024Structure of human DPPA3 bound to the UHRF1 PHD finger reveals its functional and structural differences from mouse DPPA3.0
310189662019Stella protein facilitates DNA demethylation by disrupting the chromatin association of the RING finger-type E3 ubiquitin ligase UHRF1.20
310189662019Stella protein facilitates DNA demethylation by disrupting the chromatin association of the RING finger-type E3 ubiquitin ligase UHRF1.20
276814172016Super-Enhancers at the Nanog Locus Differentially Regulate Neighboring Pluripotency-Associated Genes.63
277944802016Pluripotency induction in HEK293T cells by concurrent expression of STELLA, OCT4 and NANOS2.0
276814172016Super-Enhancers at the Nanog Locus Differentially Regulate Neighboring Pluripotency-Associated Genes.63
277944802016Pluripotency induction in HEK293T cells by concurrent expression of STELLA, OCT4 and NANOS2.0
266080312015Global DNA hypomethylation coupled to cellular transformation and metastatic ability.4
266080312015Global DNA hypomethylation coupled to cellular transformation and metastatic ability.4
252809942014Inhibition of maintenance DNA methylation by Stella.20
252809942014Inhibition of maintenance DNA methylation by Stella.20
234576362013STELLA facilitates differentiation of germ cell and endodermal lineages of human embryonic stem cells.21
234576362013STELLA facilitates differentiation of germ cell and endodermal lineages of human embryonic stem cells.21
171432672007PGC7/Stella protects against DNA demethylation in early embryogenesis.215

Citation

Dessen P

DPPA3 (developmental pluripotency associated 3)

Atlas Genet Cytogenet Oncol Haematol. 2007-04-01

Online version: http://atlasgeneticsoncology.org/gene/47240/case-report-explorer/img/favicon/favicon-16x16.png