Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 54788
MIM: 608376
HGNC: 14891
Ensembl: ENSG00000148719
Variants:
dbSNP: 54788
ClinVar: 54788
TCGA: ENSG00000148719
COSMIC: DNAJB12
RNA/Proteins
Expression (GTEx)
Pathways
| Pathway | Source | External ID |
|---|---|---|
| Protein processing in endoplasmic reticulum | KEGG | ko04141 |
| Protein processing in endoplasmic reticulum | KEGG | hsa04141 |
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 37925033 | 2024 | DNAJB12 and DNJB14 are non-redundant Hsp40 redox chaperones involved in endoplasmic reticulum protein reflux. | 0 |
| 37925033 | 2024 | DNAJB12 and DNJB14 are non-redundant Hsp40 redox chaperones involved in endoplasmic reticulum protein reflux. | 0 |
| 27916661 | 2017 | Tetrameric Assembly of K(+) Channels Requires ER-Located Chaperone Proteins. | 36 |
| 28536268 | 2017 | Endoplasmic reticulum stress-induced degradation of DNAJB12 stimulates BOK accumulation and primes cancer cells for apoptosis. | 21 |
| 27916661 | 2017 | Tetrameric Assembly of K(+) Channels Requires ER-Located Chaperone Proteins. | 36 |
| 28536268 | 2017 | Endoplasmic reticulum stress-induced degradation of DNAJB12 stimulates BOK accumulation and primes cancer cells for apoptosis. | 21 |
| 24732912 | 2014 | Expression of DNAJB12 or DNAJB14 causes coordinate invasion of the nucleus by membranes associated with a novel nuclear pore structure. | 10 |
| 24732912 | 2014 | Expression of DNAJB12 or DNAJB14 causes coordinate invasion of the nucleus by membranes associated with a novel nuclear pore structure. | 10 |
| 21148293 | 2011 | The endoplasmic reticulum-associated Hsp40 DNAJB12 and Hsc70 cooperate to facilitate RMA1 E3-dependent degradation of nascent CFTRDeltaF508. | 82 |
| 21148293 | 2011 | The endoplasmic reticulum-associated Hsp40 DNAJB12 and Hsc70 cooperate to facilitate RMA1 E3-dependent degradation of nascent CFTRDeltaF508. | 82 |
| 21150129 | 2010 | A novel ER J-protein DNAJB12 accelerates ER-associated degradation of membrane proteins including CFTR. | 40 |
| 21150129 | 2010 | A novel ER J-protein DNAJB12 accelerates ER-associated degradation of membrane proteins including CFTR. | 40 |
Citation
Dessen P
DNAJB12 (DnaJ heat shock protein family (Hsp40) member B12)
Atlas Genet Cytogenet Oncol Haematol. 2007-04-01
Online version: http://atlasgeneticsoncology.org/gene/47243/dnajb12
