Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 5999
MIM: 602516
HGNC: 10000
Ensembl: ENSG00000117152
Variants:
dbSNP: 5999
ClinVar: 5999
TCGA: ENSG00000117152
COSMIC: RGS4
RNA/Proteins
Expression (GTEx)
Pathways
PharmGKB
| Entity ID | Name | Type | Evidence | Association | PK | PD | PMIDs |
|---|---|---|---|---|---|---|---|
| PA447216 | Schizophrenia | Disease | ClinicalAnnotation, VariantAnnotation | associated | PD | 18204343 | |
| PA450688 | olanzapine | Chemical | ClinicalAnnotation | associated | PD | ||
| PA450882 | perphenazine | Chemical | ClinicalAnnotation | associated | PD | ||
| PA451201 | quetiapine | Chemical | ClinicalAnnotation | associated | PD | ||
| PA451257 | risperidone | Chemical | ClinicalAnnotation, VariantAnnotation | associated | PD | 18204343 | |
| PA451974 | ziprasidone | Chemical | ClinicalAnnotation | associated | PD | ||
| PA452233 | antipsychotics | Chemical | ClinicalAnnotation | associated | PD |
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38432633 | 2024 | RGS4 controls airway hyperresponsiveness through GAP-independent mechanisms. | 0 |
| 38432633 | 2024 | RGS4 controls airway hyperresponsiveness through GAP-independent mechanisms. | 0 |
| 34767639 | 2023 | Regulator of G-Protein Signalling 4 (RGS4) negatively modulates nociceptin/orphanin FQ opioid receptor signalling: Implication for l-Dopa-induced dyskinesia. | 1 |
| 37047106 | 2023 | Cardiac RGS Proteins in Human Heart Failure and Atrial Fibrillation: Focus on RGS4. | 4 |
| 34767639 | 2023 | Regulator of G-Protein Signalling 4 (RGS4) negatively modulates nociceptin/orphanin FQ opioid receptor signalling: Implication for l-Dopa-induced dyskinesia. | 1 |
| 37047106 | 2023 | Cardiac RGS Proteins in Human Heart Failure and Atrial Fibrillation: Focus on RGS4. | 4 |
| 35628613 | 2022 | Regulator of G-Protein Signaling-4 Attenuates Cardiac Adverse Remodeling and Neuronal Norepinephrine Release-Promoting Free Fatty Acid Receptor FFAR3 Signaling. | 12 |
| 35628613 | 2022 | Regulator of G-Protein Signaling-4 Attenuates Cardiac Adverse Remodeling and Neuronal Norepinephrine Release-Promoting Free Fatty Acid Receptor FFAR3 Signaling. | 12 |
| 31386272 | 2020 | A highly conserved δ-opioid receptor region determines RGS4 interaction. | 2 |
| 31587286 | 2020 | lncRNA RPL34-AS1 inhibits cell proliferation and invasion while promoting apoptosis by competitively binding miR-3663-3p/RGS4 in papillary thyroid cancer. | 21 |
| 32199913 | 2020 | RGS4 promotes allergen- and aspirin-associated airway hyperresponsiveness by inhibiting PGE2 biosynthesis. | 9 |
| 32386256 | 2020 | miR-874-3p inhibits cell migration through targeting RGS4 in osteosarcoma. | 13 |
| 32392739 | 2020 | Targeting RGS4 Ablates Glioblastoma Proliferation. | 13 |
| 32501280 | 2020 | RGS4 controls Gαi3-mediated regulation of Bcl-2 phosphorylation on TGN38-containing intracellular membranes. | 5 |
| 32517689 | 2020 | Regulators of G-protein signaling, RGS2 and RGS4, inhibit protease-activated receptor 4-mediated signaling by forming a complex with the receptor and Gα in live cells. | 13 |
Citation
Dessen P
RGS4 (regulator of G protein signaling 4)
Atlas Genet Cytogenet Oncol Haematol. 2007-04-01
Online version: http://atlasgeneticsoncology.org/gene/47334/rgs4
