Identity
HGNC
LOCATION
6q25.1
LOCUSID
ALIAS
FTHFSDC1,MTC1THFS,dJ292B18.2
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 25902
MIM: 611427
HGNC: 21055
Ensembl: ENSG00000120254
Variants:
dbSNP: 25902
ClinVar: 25902
TCGA: ENSG00000120254
COSMIC: MTHFD1L
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 34908119 | 2022 | Integrative analysis reveals methylenetetrahydrofolate dehydrogenase 1-like as an independent shared diagnostic and prognostic biomarker in five different human cancers. | 16 |
| 35459186 | 2022 | Circular RNA circ-MTHFD1L induces HR repair to promote gemcitabine resistance via the miR-615-3p/RPN6 axis in pancreatic ductal adenocarcinoma. | 16 |
| 34908119 | 2022 | Integrative analysis reveals methylenetetrahydrofolate dehydrogenase 1-like as an independent shared diagnostic and prognostic biomarker in five different human cancers. | 16 |
| 35459186 | 2022 | Circular RNA circ-MTHFD1L induces HR repair to promote gemcitabine resistance via the miR-615-3p/RPN6 axis in pancreatic ductal adenocarcinoma. | 16 |
| 32456526 | 2020 | MTHFD1L as a folate cycle enzyme correlates with prognostic outcome and its knockdown impairs cell invasive behaviors in osteosarcoma via mediating the AKT/mTOR pathway. | 4 |
| 32456526 | 2020 | MTHFD1L as a folate cycle enzyme correlates with prognostic outcome and its knockdown impairs cell invasive behaviors in osteosarcoma via mediating the AKT/mTOR pathway. | 4 |
| 31363079 | 2019 | Sequence variation at the MTHFD1L-AKAP12 and FOPNL loci does not influence multiple myeloma survival in Sweden. | 1 |
| 31363079 | 2019 | Sequence variation at the MTHFD1L-AKAP12 and FOPNL loci does not influence multiple myeloma survival in Sweden. | 1 |
| 29171320 | 2018 | The role of mitochondrial folate enzyme MTHFD1L in esophageal squamous cell carcinoma. | 12 |
| 29171320 | 2018 | The role of mitochondrial folate enzyme MTHFD1L in esophageal squamous cell carcinoma. | 12 |
| 28394261 | 2017 | Folate cycle enzyme MTHFD1L confers metabolic advantages in hepatocellular carcinoma. | 64 |
| 28394261 | 2017 | Folate cycle enzyme MTHFD1L confers metabolic advantages in hepatocellular carcinoma. | 64 |
| 26926881 | 2016 | Distinct effects of folate pathway genes MTHFR and MTHFD1L on ruminative response style: a potential risk mechanism for depression. | 10 |
| 26926881 | 2016 | Distinct effects of folate pathway genes MTHFR and MTHFD1L on ruminative response style: a potential risk mechanism for depression. | 10 |
| 25809277 | 2015 | Rs6922269 marker at the MTHFD1L gene predict cardiovascular mortality in males after acute coronary syndrome. | 4 |
Citation
Dessen P
MTHFD1L (methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1 like)
Atlas Genet Cytogenet Oncol Haematol. 2007-04-01
Online version: http://atlasgeneticsoncology.org/gene/47403/mthfd1l
