Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 5502
MIM: 613246
HGNC: 9286
Ensembl: ENSG00000135447
Variants:
dbSNP: 5502
ClinVar: 5502
TCGA: ENSG00000135447
COSMIC: PPP1R1A
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000135447 | ENST00000257905 | Q13522 |
| ENSG00000135447 | ENST00000547431 | R4GMQ8 |
| ENSG00000135447 | ENST00000547826 | F8VR76 |
| ENSG00000135447 | ENST00000553113 | H0YIU4 |
Expression (GTEx)
Pathways
| Pathway | Source | External ID |
|---|---|---|
| Long-term potentiation | KEGG | ko04720 |
| Long-term potentiation | KEGG | hsa04720 |
| Adrenergic signaling in cardiomyocytes | KEGG | hsa04261 |
| Adrenergic signaling in cardiomyocytes | KEGG | ko04261 |
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38574885 | 2024 | Unraveling the significance of PPP1R1A gene in pancreatic β-cell function: A study in INS-1 cells and human pancreatic islets. | 0 |
| 38574885 | 2024 | Unraveling the significance of PPP1R1A gene in pancreatic β-cell function: A study in INS-1 cells and human pancreatic islets. | 0 |
| 36018458 | 2022 | Exploring prognostic value and regulation network of PPP1R1A in hepatocellular carcinoma. | 0 |
| 36018458 | 2022 | Exploring prognostic value and regulation network of PPP1R1A in hepatocellular carcinoma. | 0 |
| 33631146 | 2021 | The MafA-target gene PPP1R1A regulates GLP1R-mediated amplification of glucose-stimulated insulin secretion in β-cells. | 10 |
| 33631146 | 2021 | The MafA-target gene PPP1R1A regulates GLP1R-mediated amplification of glucose-stimulated insulin secretion in β-cells. | 10 |
| 31797701 | 2020 | A Novel lncRNA HOXC-AS3 Acts as a miR-3922-5p Sponge to Promote Breast Cancer Metastasis. | 12 |
| 31797701 | 2020 | A Novel lncRNA HOXC-AS3 Acts as a miR-3922-5p Sponge to Promote Breast Cancer Metastasis. | 12 |
| 29059150 | 2018 | Protein phosphatase 1 regulatory subunit 1A in ewing sarcoma tumorigenesis and metastasis. | 33 |
| 29059150 | 2018 | Protein phosphatase 1 regulatory subunit 1A in ewing sarcoma tumorigenesis and metastasis. | 33 |
| 26455482 | 2015 | Human G109E-inhibitor-1 impairs cardiac function and promotes arrhythmias. | 9 |
| 26455482 | 2015 | Human G109E-inhibitor-1 impairs cardiac function and promotes arrhythmias. | 9 |
| 24249716 | 2014 | Synergistic role of protein phosphatase inhibitor 1 and sarco/endoplasmic reticulum Ca2+ -ATPase in the acquisition of the contractile phenotype of arterial smooth muscle cells. | 12 |
| 24249716 | 2014 | Synergistic role of protein phosphatase inhibitor 1 and sarco/endoplasmic reticulum Ca2+ -ATPase in the acquisition of the contractile phenotype of arterial smooth muscle cells. | 12 |
| 20628086 | 2010 | Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study. | 15 |
Citation
Dessen P
PPP1R1A (protein phosphatase 1 regulatory inhibitor subunit 1A)
Atlas Genet Cytogenet Oncol Haematol. 2007-04-01
Online version: http://atlasgeneticsoncology.org/gene/47409/ppp1r1a
