NCOA7 (nuclear receptor coactivator 7)

2007-04-01  

Identity

HGNC
NCOA7
LOCATION
6q22.31
LOCUSID
135112
ALIAS
ERAP140,ESNA1,NCOA7-AS,Nbla00052,Nbla10993,TLDC4,dJ187J11.3
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 135112
MIM: 609752
HGNC: 21081
Ensembl: ENSG00000111912

Variants:

dbSNP: 135112
ClinVar: 135112
TCGA: ENSG00000111912
COSMIC: NCOA7

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000111912ENST00000229634Q8NI08
ENSG00000111912ENST00000368357Q8NI08
ENSG00000111912ENST00000392477Q8NI08
ENSG00000111912ENST00000417494Q5TF96
ENSG00000111912ENST00000419660Q5TF97
ENSG00000111912ENST00000428318Q5TF98
ENSG00000111912ENST00000438495Q8NI08
ENSG00000111912ENST00000438495H0Y5F6
ENSG00000111912ENST00000444128H0Y6T0
ENSG00000111912ENST00000453302Q5TF98

Expression (GTEx)

0
5
10
15
20
25
30
35
40
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
375113432023NCOA7 Regulates Growth and Metastasis of Clear Cell Renal Cell Carcinoma via MAPK/ERK Signaling Pathway.3
375113432023NCOA7 Regulates Growth and Metastasis of Clear Cell Renal Cell Carcinoma via MAPK/ERK Signaling Pathway.3
343411882021Crystal structure of the TLDc domain of human NCOA7-AS.5
348079542021TMPRSS2 promotes SARS-CoV-2 evasion from NCOA7-mediated restriction.14
343411882021Crystal structure of the TLDc domain of human NCOA7-AS.5
348079542021TMPRSS2 promotes SARS-CoV-2 evasion from NCOA7-mediated restriction.14
307000042019Overexpression of the Interferon-Inducible Isoform 4 of NCOA7 Dissects the Entry Route of Enveloped Viruses and Demonstrates that HIV Enters Cells via Fusion at the Plasma Membrane.1
314819622019Engagement of Nuclear Coactivator 7 by 3-Hydroxyanthranilic Acid Enhances Activation of Aryl Hydrocarbon Receptor in Immunoregulatory Dendritic Cells.30
307000042019Overexpression of the Interferon-Inducible Isoform 4 of NCOA7 Dissects the Entry Route of Enveloped Viruses and Demonstrates that HIV Enters Cells via Fusion at the Plasma Membrane.1
314819622019Engagement of Nuclear Coactivator 7 by 3-Hydroxyanthranilic Acid Enhances Activation of Aryl Hydrocarbon Receptor in Immunoregulatory Dendritic Cells.30
275090542016MALDI imaging reveals NCOA7 as a potential biomarker in oral squamous cell carcinoma arising from oral submucous fibrosis.16
275090542016MALDI imaging reveals NCOA7 as a potential biomarker in oral squamous cell carcinoma arising from oral submucous fibrosis.16
216101082011A multistage association study identifies a breast cancer genetic locus at NCOA7.13
216101082011A multistage association study identifies a breast cancer genetic locus at NCOA7.13
184979402008ERAP140/Nbla10993 is a novel favorable prognostic indicator for neuroblastoma induced in response to retinoic acid.7

Citation

Dessen P

NCOA7 (nuclear receptor coactivator 7)

Atlas Genet Cytogenet Oncol Haematol. 2007-04-01

Online version: http://atlasgeneticsoncology.org/gene/47414