HES4 (hes family bHLH transcription factor 4)

2007-04-01  

Identity

HGNC
HES4
LOCATION
1p36.33
LOCUSID
57801
ALIAS
bHLHb42

Other Information

Locus ID:

NCBI: 57801
MIM: 608060
HGNC: 24149
Ensembl: ENSG00000188290

Variants:

dbSNP: 57801
ClinVar: 57801
TCGA: ENSG00000188290
COSMIC: HES4

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000188290ENST00000304952Q9HCC6
ENSG00000188290ENST00000428771E9PB28
ENSG00000188290ENST00000484667D6REB3

Expression (GTEx)

0
10
20
30
40
50
60
70
80
90
100
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

References

Pubmed IDYearTitleCitations
319190812021HES1 and HES4 have non-redundant roles downstream of Notch during early human T-cell development.16
319190812021HES1 and HES4 have non-redundant roles downstream of Notch during early human T-cell development.16
277864112017Hes4: A potential prognostic biomarker for newly diagnosed patients with high-grade osteosarcoma.13
277864112017Hes4: A potential prognostic biomarker for newly diagnosed patients with high-grade osteosarcoma.13
254808892015Epigenetic dysregulation of hairy and enhancer of split 4 (HES4) is associated with striatal degeneration in postmortem Huntington brains.35
255792202015Novel basic helix-loop-helix transcription factor hes4 antagonizes the function of twist-1 to regulate lineage commitment of bone marrow stromal/stem cells.18
254808892015Epigenetic dysregulation of hairy and enhancer of split 4 (HES4) is associated with striatal degeneration in postmortem Huntington brains.35
255792202015Novel basic helix-loop-helix transcription factor hes4 antagonizes the function of twist-1 to regulate lineage commitment of bone marrow stromal/stem cells.18

Citation

Dessen P

HES4 (hes family bHLH transcription factor 4)

Atlas Genet Cytogenet Oncol Haematol. 2007-04-01

Online version: http://atlasgeneticsoncology.org/gene/47428