Identity
HGNC
LOCATION
1p35.3
LOCUSID
ALIAS
HI95,SES2,SEST2
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 83667
MIM: 607767
HGNC: 20746
Ensembl: ENSG00000130766
Variants:
dbSNP: 83667
ClinVar: 83667
TCGA: ENSG00000130766
COSMIC: SESN2
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000130766 | ENST00000253063 | P58004 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38165565 | 2024 | Sestrin2 ameliorates diabetic retinopathy by regulating autophagy and ferroptosis. | 2 |
| 38331008 | 2024 | Sestrin2 reduces ferroptosis via the Keap1/Nrf2 signaling pathway after intestinal ischemia-reperfusion. | 1 |
| 38379215 | 2024 | Sestrin 2 protects human lens epithelial cells from oxidative stress and apoptosis induced by hydrogen peroxide by regulating the mTOR/Nrf2 pathway. | 0 |
| 38165565 | 2024 | Sestrin2 ameliorates diabetic retinopathy by regulating autophagy and ferroptosis. | 2 |
| 38331008 | 2024 | Sestrin2 reduces ferroptosis via the Keap1/Nrf2 signaling pathway after intestinal ischemia-reperfusion. | 1 |
| 38379215 | 2024 | Sestrin 2 protects human lens epithelial cells from oxidative stress and apoptosis induced by hydrogen peroxide by regulating the mTOR/Nrf2 pathway. | 0 |
| 36066109 | 2023 | Sestrin2 suppresses ferroptosis to alleviate septic intestinal inflammation and barrier dysfunction. | 3 |
| 36620877 | 2023 | Sestrin2 mediates FOXM1 expression to block the EMT process in non-small cell lung cancer through the AMPK/YAP pathway. | 1 |
| 36841824 | 2023 | Sestrin2: multifaceted functions, molecular basis, and its implications in liver diseases. | 5 |
| 36902310 | 2023 | Sestrin2 as a Protective Shield against Cardiovascular Disease. | 1 |
| 36980973 | 2023 | SESN2 Could Be a Potential Marker for Diagnosis and Prognosis in Glioma. | 1 |
| 37918578 | 2023 | Genetic variations in a Sestrin2/Sestrin3/mTOR Axis and development of new-onset diabetes after kidney transplantation. | 0 |
| 38031041 | 2023 | Significance of serum sestrin2 as a biomarker of severity and functional outcome in acute intracerebral hemorrhage: a prospective observational longitudinal study. | 0 |
| 36066109 | 2023 | Sestrin2 suppresses ferroptosis to alleviate septic intestinal inflammation and barrier dysfunction. | 3 |
| 36620877 | 2023 | Sestrin2 mediates FOXM1 expression to block the EMT process in non-small cell lung cancer through the AMPK/YAP pathway. | 1 |
Citation
Dessen P
SESN2 (sestrin 2)
Atlas Genet Cytogenet Oncol Haematol. 2007-04-01
Online version: http://atlasgeneticsoncology.org/gene/47453/sesn2
