Identity
HGNC
LOCATION
12q13.11
LOCUSID
ALIAS
ATP-PFK,GSD7,PFK-1,PFK-A,PFK1,PFKA,PFKX,PPP1R122
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 5213
MIM: 610681
HGNC: 8877
Ensembl: ENSG00000152556
Variants:
dbSNP: 5213
ClinVar: 5213
TCGA: ENSG00000152556
COSMIC: PFKM
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 36601784 | 2023 | RNAi screening reveals a synthetic chemical-genetic interaction between ATP synthase and PFK1 in cancer cells. | 2 |
| 37622331 | 2023 | Cancer-associated somatic mutations in human phosphofructokinase-1 reveal a critical electrostatic interaction for allosteric regulation of enzyme activity. | 2 |
| 36601784 | 2023 | RNAi screening reveals a synthetic chemical-genetic interaction between ATP synthase and PFK1 in cancer cells. | 2 |
| 37622331 | 2023 | Cancer-associated somatic mutations in human phosphofructokinase-1 reveal a critical electrostatic interaction for allosteric regulation of enzyme activity. | 2 |
| 35328104 | 2022 | Expression of HK2, PKM2, and PFKM Is Associated with Metastasis and Late Disease Onset in Breast Cancer Patients. | 6 |
| 35838787 | 2022 | Association of PFKM gene polymorphisms and susceptibility to cryptorchidism in a Chinese Han population. | 0 |
| 36253358 | 2022 | Bone marrow mesenchymal stem cell-derived exosomal miR-21a-5p alleviates renal fibrosis by attenuating glycolysis by targeting PFKM. | 7 |
| 35328104 | 2022 | Expression of HK2, PKM2, and PFKM Is Associated with Metastasis and Late Disease Onset in Breast Cancer Patients. | 6 |
| 35838787 | 2022 | Association of PFKM gene polymorphisms and susceptibility to cryptorchidism in a Chinese Han population. | 0 |
| 36253358 | 2022 | Bone marrow mesenchymal stem cell-derived exosomal miR-21a-5p alleviates renal fibrosis by attenuating glycolysis by targeting PFKM. | 7 |
| 33404290 | 2021 | RNAi-mediated knockdown of PFK1 decreases the invasive capability and metastasis of nasopharyngeal carcinoma cell line, CNE-2. | 5 |
| 33516882 | 2021 | PFK activation is essential for the odontogenic differentiation of human dental pulp stem cells. | 2 |
| 33897890 | 2021 | ZEB1 enhances Warburg effect to facilitate tumorigenesis and metastasis of HCC by transcriptionally activating PFKM. | 38 |
| 33404290 | 2021 | RNAi-mediated knockdown of PFK1 decreases the invasive capability and metastasis of nasopharyngeal carcinoma cell line, CNE-2. | 5 |
| 33516882 | 2021 | PFK activation is essential for the odontogenic differentiation of human dental pulp stem cells. | 2 |
Citation
Dessen P
PFKM (phosphofructokinase, muscle)
Atlas Genet Cytogenet Oncol Haematol. 2007-04-01
Online version: http://atlasgeneticsoncology.org/gene/47486/pfkm
