Identity
HGNC
LOCATION
17p13.2
LOCUSID
ALIAS
ACKR6,CORD5,NIR1,RDGBA3
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 83394
MIM: 608921
HGNC: 21043
Ensembl: ENSG00000091622
Variants:
dbSNP: 83394
ClinVar: 83394
TCGA: ENSG00000091622
COSMIC: PITPNM3
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000091622 | ENST00000262483 | Q9BZ71 |
| ENSG00000091622 | ENST00000421306 | Q9BZ71 |
| ENSG00000091622 | ENST00000575201 | I3L1K1 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 35041514 | 2022 | Chemokine CCL18 Promotes Phagocytosis Through Its Receptor CCR8 Rather than PITPNM3 in Human Microglial Cells. | 0 |
| 35041514 | 2022 | Chemokine CCL18 Promotes Phagocytosis Through Its Receptor CCR8 Rather than PITPNM3 in Human Microglial Cells. | 0 |
| 31955176 | 2020 | Mitofusin-2 (Mfn-2) Might Have Anti-Cancer Effect through Interaction with Transcriptional Factor SP1 and Consequent Regulation on Phosphatidylinositol Transfer Protein 3 (PITPNM3) Expression. | 2 |
| 32641093 | 2020 | CCL18-NIR1 promotes oral cancer cell growth and metastasis by activating the JAK2/STAT3 signaling pathway. | 18 |
| 31955176 | 2020 | Mitofusin-2 (Mfn-2) Might Have Anti-Cancer Effect through Interaction with Transcriptional Factor SP1 and Consequent Regulation on Phosphatidylinositol Transfer Protein 3 (PITPNM3) Expression. | 2 |
| 32641093 | 2020 | CCL18-NIR1 promotes oral cancer cell growth and metastasis by activating the JAK2/STAT3 signaling pathway. | 18 |
| 26449829 | 2016 | CCL18/PITPNM3 enhances migration, invasion, and EMT through the NF-κB signaling pathway in hepatocellular carcinoma. | 34 |
| 26756176 | 2016 | CC chemokine ligand 18(CCL18) promotes migration and invasion of lung cancer cells by binding to Nir1 through Nir1-ELMO1/DOC180 signaling pathway. | 32 |
| 26449829 | 2016 | CCL18/PITPNM3 enhances migration, invasion, and EMT through the NF-κB signaling pathway in hepatocellular carcinoma. | 34 |
| 26756176 | 2016 | CC chemokine ligand 18(CCL18) promotes migration and invasion of lung cancer cells by binding to Nir1 through Nir1-ELMO1/DOC180 signaling pathway. | 32 |
| 22405330 | 2013 | Ocular phenotype of CORD5, an autosomal dominant retinal dystrophy associated with PITPNM3 p.Q626H mutation. | 5 |
| 24001613 | 2013 | Nir1 promotes invasion of breast cancer cells by binding to chemokine (C-C motif) ligand 18 through the PI3K/Akt/GSK3β/Snail signalling pathway. | 38 |
| 22405330 | 2013 | Ocular phenotype of CORD5, an autosomal dominant retinal dystrophy associated with PITPNM3 p.Q626H mutation. | 5 |
| 24001613 | 2013 | Nir1 promotes invasion of breast cancer cells by binding to chemokine (C-C motif) ligand 18 through the PI3K/Akt/GSK3β/Snail signalling pathway. | 38 |
| 21481794 | 2011 | CCL18 from tumor-associated macrophages promotes breast cancer metastasis via PITPNM3. | 311 |
Citation
Dessen P
PITPNM3 (PITPNM family member 3)
Atlas Genet Cytogenet Oncol Haematol. 2007-04-01
Online version: http://atlasgeneticsoncology.org/gene/47499/pitpnm3
