Identity
HGNC
LOCATION
2p25.1
LOCUSID
ALIAS
RNF144,UBCE7IP4,hUIP4
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 9781
HGNC: 20457
Ensembl: ENSG00000151692
Variants:
dbSNP: 9781
ClinVar: 9781
TCGA: ENSG00000151692
COSMIC: RNF144A
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000151692 | ENST00000320892 | P50876 |
| ENSG00000151692 | ENST00000416587 | C9JLH4 |
| ENSG00000151692 | ENST00000432850 | H7C3G0 |
| ENSG00000151692 | ENST00000433456 | C9JLH4 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
PharmGKB
| Entity ID | Name | Type | Evidence | Association | PK | PD | PMIDs |
|---|---|---|---|---|---|---|---|
| PA166128121 | cardiotoxicity | Disease | MultilinkAnnotation | associated | 26340055 |
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 35103856 | 2022 | RNF144A exerts tumor suppressor function in breast cancer through targeting YY1 for proteasomal degradation to downregulate GMFG expression. | 5 |
| 35103856 | 2022 | RNF144A exerts tumor suppressor function in breast cancer through targeting YY1 for proteasomal degradation to downregulate GMFG expression. | 5 |
| 31406303 | 2020 | RNF144A functions as a tumor suppressor in breast cancer through ubiquitin ligase activity-dependent regulation of stability and oncogenic functions of HSPA2. | 31 |
| 32557973 | 2020 | Solution structure of the zinc finger domain of human RNF144A ubiquitin ligase. | 1 |
| 33067254 | 2020 | RNF144a induces ERK-dependent cell death under oxidative stress via downregulation of vaccinia-related kinase 3. | 3 |
| 31406303 | 2020 | RNF144A functions as a tumor suppressor in breast cancer through ubiquitin ligase activity-dependent regulation of stability and oncogenic functions of HSPA2. | 31 |
| 32557973 | 2020 | Solution structure of the zinc finger domain of human RNF144A ubiquitin ligase. | 1 |
| 33067254 | 2020 | RNF144a induces ERK-dependent cell death under oxidative stress via downregulation of vaccinia-related kinase 3. | 3 |
| 29473320 | 2018 | Epigenetic silencing of RNF144A expression in breast cancer cells through promoter hypermethylation and MBD4. | 11 |
| 30171075 | 2018 | RNF144A sustains EGFR signaling to promote EGF-dependent cell proliferation. | 10 |
| 29473320 | 2018 | Epigenetic silencing of RNF144A expression in breast cancer cells through promoter hypermethylation and MBD4. | 11 |
| 30171075 | 2018 | RNF144A sustains EGFR signaling to promote EGF-dependent cell proliferation. | 10 |
| 26216882 | 2015 | Regulation of RNF144A E3 Ubiquitin Ligase Activity by Self-association through Its Transmembrane Domain. | 15 |
| 26216882 | 2015 | Regulation of RNF144A E3 Ubiquitin Ligase Activity by Self-association through Its Transmembrane Domain. | 15 |
| 24979766 | 2014 | RNF144A, an E3 ubiquitin ligase for DNA-PKcs, promotes apoptosis during DNA damage. | 44 |
Citation
Dessen P
RNF144A (ring finger protein 144A)
Atlas Genet Cytogenet Oncol Haematol. 2007-04-01
Online version: http://atlasgeneticsoncology.org/gene/47523/rnf144a
