NID2 (nidogen 2)

2007-05-01  

Identity

HGNC
NID2
LOCATION
14q22.1
LOCUSID
22795
ALIAS
NID-2
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 22795
MIM: 605399
HGNC: 13389
Ensembl: ENSG00000087303

Variants:

dbSNP: 22795
ClinVar: 22795
TCGA: ENSG00000087303
COSMIC: NID2

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000087303ENST00000216286Q14112
ENSG00000087303ENST00000556572H0YJV3
ENSG00000087303ENST00000617139A0A087WZP6

Expression (GTEx)

0
50
100
150
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
Extracellular matrix organizationREACTOMER-HSA-1474244
Laminin interactionsREACTOMER-HSA-3000157

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
345936722022Nidogen-2: A new biomarker in colon cancer patients.1
345936722022Nidogen-2: A new biomarker in colon cancer patients.1
337581602021Genome-Scale Analysis Identified NID2, SPARC, and MFAP2 as Prognosis Markers of Overall Survival in Gastric Cancer.11
343152242021Nidogen-2 Maintains the Contractile Phenotype of Vascular Smooth Muscle Cells and Prevents Neointima Formation via Bridging Jagged1-Notch3 Signaling.19
337581602021Genome-Scale Analysis Identified NID2, SPARC, and MFAP2 as Prognosis Markers of Overall Survival in Gastric Cancer.11
343152242021Nidogen-2 Maintains the Contractile Phenotype of Vascular Smooth Muscle Cells and Prevents Neointima Formation via Bridging Jagged1-Notch3 Signaling.19
308269722020Silencing NID2 by DNA Hypermethylation Promotes Lung Cancer.9
321712892020Evaluation of NID2 promoter methylation for screening of Oral squamous cell carcinoma.10
324721132020A pilot proteomic study with a prospective cohort suspected to develop preeclampsia.0
308269722020Silencing NID2 by DNA Hypermethylation Promotes Lung Cancer.9
321712892020Evaluation of NID2 promoter methylation for screening of Oral squamous cell carcinoma.10
324721132020A pilot proteomic study with a prospective cohort suspected to develop preeclampsia.0
309754892019Integrated bioinformatics analysis reveals novel key biomarkers and potential candidate small molecule drugs in gastric cancer.16
313628882019NID2 can serve as a potential prognosis prediction biomarker and promotes the invasion and migration of gastric cancer.13
309754892019Integrated bioinformatics analysis reveals novel key biomarkers and potential candidate small molecule drugs in gastric cancer.16

Citation

Dessen P

NID2 (nidogen 2)

Atlas Genet Cytogenet Oncol Haematol. 2007-05-01

Online version: http://atlasgeneticsoncology.org/gene/47531