Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 9075
MIM: 300520
HGNC: 2041
Ensembl: ENSG00000165376
Variants:
dbSNP: 9075
ClinVar: 9075
TCGA: ENSG00000165376
COSMIC: CLDN2
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000165376 | ENST00000336803 | P57739 |
| ENSG00000165376 | ENST00000540876 | P57739 |
| ENSG00000165376 | ENST00000541806 | P57739 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38056686 | 2024 | Plasma-activated medium ameliorates the chemoresistance of human lung adenocarcinoma cells mediated via downregulation of claudin-2 expression. | 0 |
| 38056686 | 2024 | Plasma-activated medium ameliorates the chemoresistance of human lung adenocarcinoma cells mediated via downregulation of claudin-2 expression. | 0 |
| 36961882 | 2023 | Downregulation of angulin-1/LSR induces malignancy via upregulation of EGF-dependent claudin-2 and TGF-β-dependent cell metabolism in human lung adenocarcinoma A549 cells. | 2 |
| 37147871 | 2023 | Claudin-2 in hyperproliferative migrating keratinocytes and migration inhibition via siRNA knockdown. | 0 |
| 36961882 | 2023 | Downregulation of angulin-1/LSR induces malignancy via upregulation of EGF-dependent claudin-2 and TGF-β-dependent cell metabolism in human lung adenocarcinoma A549 cells. | 2 |
| 37147871 | 2023 | Claudin-2 in hyperproliferative migrating keratinocytes and migration inhibition via siRNA knockdown. | 0 |
| 35896264 | 2022 | Chitinase 3-like 1, Carcinoembryonic Antigen-related Cell Adhesion Molecule 6, and Ectopic Claudin-2 in the Carcinogenic Processes of Ulcerative Colitis. | 2 |
| 35968893 | 2022 | Loss of NKCC1 function increases epithelial tight junction permeability by upregulating claudin-2 expression. | 2 |
| 35896264 | 2022 | Chitinase 3-like 1, Carcinoembryonic Antigen-related Cell Adhesion Molecule 6, and Ectopic Claudin-2 in the Carcinogenic Processes of Ulcerative Colitis. | 2 |
| 35968893 | 2022 | Loss of NKCC1 function increases epithelial tight junction permeability by upregulating claudin-2 expression. | 2 |
| 33419064 | 2021 | Down-Regulation of Claudin-2 Expression by Cyanidin-3-Glucoside Enhances Sensitivity to Anticancer Drugs in the Spheroid of Human Lung Adenocarcinoma A549 Cells. | 7 |
| 33932903 | 2021 | LncRNA NKILA knockdown promotes cell viability and represses cell apoptosis, autophagy and inflammation in lipopolysaccharide-induced sepsis model by regulating miR-140-5p/CLDN2 axis. | 13 |
| 34079064 | 2021 | Claudin-2 promotes colorectal cancer liver metastasis and is a biomarker of the replacement type growth pattern. | 24 |
| 34205320 | 2021 | Elevation of Chemosensitivity of Lung Adenocarcinoma A549 Spheroid Cells by Claudin-2 Knockdown through Activation of Glucose Transport and Inhibition of Nrf2 Signal. | 5 |
| 33419064 | 2021 | Down-Regulation of Claudin-2 Expression by Cyanidin-3-Glucoside Enhances Sensitivity to Anticancer Drugs in the Spheroid of Human Lung Adenocarcinoma A549 Cells. | 7 |
Citation
Dessen P
CLDN2 (claudin 2)
Atlas Genet Cytogenet Oncol Haematol. 2007-07-01
Online version: http://atlasgeneticsoncology.org/gene/47621/cldn2
