Identity
HGNC
LOCATION
17q23.2
LOCUSID
ALIAS
CD280,CLEC13E,ENDO180,UPARAP
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 9902
MIM: 612264
HGNC: 16875
Ensembl: ENSG00000011028
Variants:
dbSNP: 9902
ClinVar: 9902
TCGA: ENSG00000011028
COSMIC: MRC2
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000011028 | ENST00000303375 | Q9UBG0 |
| ENSG00000011028 | ENST00000446119 | E7EME3 |
| ENSG00000011028 | ENST00000579432 | J3QQZ6 |
| ENSG00000011028 | ENST00000584682 | J3KRF1 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 34012764 | 2021 | MRC2 Promotes Proliferation and Inhibits Apoptosis of Diabetic Nephropathy. | 6 |
| 34768883 | 2021 | The Collagen Receptor uPARAP in Malignant Mesothelioma: A Potential Diagnostic Marker and Therapeutic Target. | 2 |
| 34012764 | 2021 | MRC2 Promotes Proliferation and Inhibits Apoptosis of Diabetic Nephropathy. | 6 |
| 34768883 | 2021 | The Collagen Receptor uPARAP in Malignant Mesothelioma: A Potential Diagnostic Marker and Therapeutic Target. | 2 |
| 31376337 | 2020 | Interleukin-1 alpha derived from ultraviolet B-exposed keratinocytes is associated with a decrease of endocytic collagen receptor Endo180. | 1 |
| 32072971 | 2020 | Mathematical modelling of the role of Endo180 network in the development of metastatic bone disease in prostate cancer. | 4 |
| 31376337 | 2020 | Interleukin-1 alpha derived from ultraviolet B-exposed keratinocytes is associated with a decrease of endocytic collagen receptor Endo180. | 1 |
| 32072971 | 2020 | Mathematical modelling of the role of Endo180 network in the development of metastatic bone disease in prostate cancer. | 4 |
| 30366943 | 2019 | Immune regulation by fibroblasts in tissue injury depends on uPARAP-mediated uptake of collectins. | 10 |
| 30366943 | 2019 | Immune regulation by fibroblasts in tissue injury depends on uPARAP-mediated uptake of collectins. | 10 |
| 29061505 | 2018 | Pancreatic stellate cells reorganize matrix components and lead pancreatic cancer invasion via the function of Endo180. | 18 |
| 29061505 | 2018 | Pancreatic stellate cells reorganize matrix components and lead pancreatic cancer invasion via the function of Endo180. | 18 |
| 26466547 | 2016 | Targeting a novel bone degradation pathway in primary bone cancer by inactivation of the collagen receptor uPARAP/Endo180. | 16 |
| 27247422 | 2016 | Crystal structures of the ligand-binding region of uPARAP: effect of calcium ion binding. | 4 |
| 26466547 | 2016 | Targeting a novel bone degradation pathway in primary bone cancer by inactivation of the collagen receptor uPARAP/Endo180. | 16 |
Citation
Dessen P
MRC2 (mannose receptor C type 2)
Atlas Genet Cytogenet Oncol Haematol. 2007-07-01
Online version: http://atlasgeneticsoncology.org/gene/47622/mrc2
