SCG5 (secretogranin V)

2007-10-01  

Identity

HGNC
LOCATION
15q13.3
LOCUSID
ALIAS
7B2,P7B2,SGNE1,SgV
FUSION GENES

Other Information

Locus ID:

NCBI: 6447
MIM: 173120
HGNC: 10816
Ensembl: ENSG00000166922

Variants:

dbSNP: 6447
ClinVar: 6447
TCGA: ENSG00000166922
COSMIC: SCG5

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000166922ENST00000300175P05408
ENSG00000166922ENST00000300175A0A024R9I1
ENSG00000166922ENST00000413748P05408
ENSG00000166922ENST00000471027H7C4X7
ENSG00000166922ENST00000494364C9J650
ENSG00000166922ENST00000497208C9JNY7

Expression (GTEx)

0
100
200
300
400
500
600

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
279841232017Clinicopathological features of a kindred with SCG5-GREM1-associated hereditary mixed polyposis syndrome.5
279841232017Clinicopathological features of a kindred with SCG5-GREM1-associated hereditary mixed polyposis syndrome.5
258112412015Phosphorylation and Alternative Splicing of 7B2 Reduce Prohormone Convertase 2 Activation.6
258112412015Phosphorylation and Alternative Splicing of 7B2 Reduce Prohormone Convertase 2 Activation.6
231722242013The neuroendocrine protein 7B2 suppresses the aggregation of neurodegenerative disease-related proteins.28
240420522013Blockade of islet amyloid polypeptide fibrillation and cytotoxicity by the secretory chaperones 7B2 and proSAAS.18
231722242013The neuroendocrine protein 7B2 suppresses the aggregation of neurodegenerative disease-related proteins.28
240420522013Blockade of islet amyloid polypeptide fibrillation and cytotoxicity by the secretory chaperones 7B2 and proSAAS.18
219017452012Frequent epigenetic inactivation of the chaperone SGNE1/7B2 in human gliomas.3
229470852012The neuroendocrine protein 7B2 is intrinsically disordered.8
219017452012Frequent epigenetic inactivation of the chaperone SGNE1/7B2 in human gliomas.3
229470852012The neuroendocrine protein 7B2 is intrinsically disordered.8
190587892009A common variant in DRD3 receptor is associated with autism spectrum disorder.31
190587892009A common variant in DRD3 receptor is associated with autism spectrum disorder.31
184481762008Measurements of secretogranins II, III, V and proconvertases 1/3 and 2 in plasma from patients with neuroendocrine tumours.13

Citation

Dessen P

SCG5 (secretogranin V)

Atlas Genet Cytogenet Oncol Haematol. 2007-10-01

Online version: http://atlasgeneticsoncology.org/gene/49757/scg5