BTF3 (basic transcription factor 3)

2007-10-01 Affiliation

Identity

HGNC

BTF3

LOCATION

5q13.2

LOCUSID

689

ALIAS

BETA-NAC,BTF3a,BTF3b,NACB

FUSION GENES

Show Gene Fusions

Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool

Other Information

Locus ID:

NCBI: 689
MIM: 602542
HGNC: 1125
Ensembl: ENSG00000145741

Variants:

dbSNP: 689
ClinVar: 689
TCGA: ENSG00000145741
COSMIC: BTF3

RNA/Proteins

Gene ID	Transcript ID	Uniprot
ENSG00000145741	ENST00000335895	P20290
ENSG00000145741	ENST00000380591	P20290
ENSG00000145741	ENST00000507081	D6RDG3
ENSG00000145741	ENST00000509708	H0Y9Y1

Expression (GTEx)

500

1000

1500

Adipose - Subcutaneous

Adipose - Visceral

Adrenal Gland

Artery - Aorta

Artery - Tibial

Bladder

Brain - Amygdala

Brain - Anterior cingulate cortex

Brain - Caudate

Brain - Cerebellar Hemisphere

Brain - Cerebellum

Brain - Cortex

Brain - Frontal Cortex

Brain - Hippocampus

Brain - Hypothalamus

Brain - Nucleus accumbens

Brain - Putamen

Brain - Spinal cord

Brain - Substantia nigra

Breast - Mammary Tissue

Cells - Cultured fibroblasts

Cells - EBV - transformed lymphocytes

Cervix - Ectocervix

Cervix - Endocervix

Colon - Sigmoid

Colon - Transverse

Esophagus - Gastroesophageal Junction

Esophagus - Mucosa

Esophagus - Muscularis

Fallopian Tube

Heart - Atrial Appendage

Heart - Left Ventricle

Kidney - Cortex

Kidney - Medulla

Liver

Lung

Minor Salivary Gland

Muscle - Skeletal

Nerve - Tibial

Ovary

Pancreas

Pituitary

Prostate

Skin - Not Sun Exposed

Skin - Sun Exposed

Small Intestine - Terminal Ileum

Spleen

Stomach

Testis

Thyroid

Uterus

Vagina

Whole Blood

Protein levels (Protein atlas)

Not detected

Low

Medium

High

References

Pubmed ID	Year	Title	Citations
38340226	2024	Ubiquitination-specific protease 7 enhances stemness of hepatocellular carcinoma by stabilizing basic transcription factor 3.	0
38340226	2024	Ubiquitination-specific protease 7 enhances stemness of hepatocellular carcinoma by stabilizing basic transcription factor 3.	0
37382415	2023	BTF3 promotes proliferation and glycolysis in hepatocellular carcinoma by regulating GLUT1.	3
37382415	2023	BTF3 promotes proliferation and glycolysis in hepatocellular carcinoma by regulating GLUT1.	3
33383560	2021	BTF3 promotes stemness and inhibits TypeⅠInterferon signaling pathway in triple-negative breast cancer.	3
33414468	2021	BTF3 confers oncogenic activity in prostate cancer through transcriptional upregulation of Replication Factor C.	6
34293363	2021	BTF3-mediated regulation of BMI1 promotes colorectal cancer through influencing epithelial-mesenchymal transition and stem cell-like traits.	8
33383560	2021	BTF3 promotes stemness and inhibits TypeⅠInterferon signaling pathway in triple-negative breast cancer.	3
33414468	2021	BTF3 confers oncogenic activity in prostate cancer through transcriptional upregulation of Replication Factor C.	6
34293363	2021	BTF3-mediated regulation of BMI1 promotes colorectal cancer through influencing epithelial-mesenchymal transition and stem cell-like traits.	8
32582971	2020	miR‑802 inhibits the epithelial‑mesenchymal transition, migration and invasion of cervical cancer by regulating BTF3.	4
32582971	2020	miR‑802 inhibits the epithelial‑mesenchymal transition, migration and invasion of cervical cancer by regulating BTF3.	4
30315845	2019	Inhibition of BTF3 sensitizes luminal breast cancer cells to PI3Kα inhibition through the transcriptional regulation of ERα.	15
31138311	2019	BTF3 sustains cancer stem-like phenotype of prostate cancer via stabilization of BMI1.	18
31263147	2019	Positive expression of basic transcription factor 3 predicts poor survival of colorectal cancer patients: possible mechanisms involved.	4

Citation

Dessen P

BTF3 (basic transcription factor 3)

Atlas Genet Cytogenet Oncol Haematol. 2007-10-01

Online version: http://atlasgeneticsoncology.org/gene/49761/meetings/gene-fusions/js/lib/deep-insight-explorer/