Identity
HGNC
LOCATION
5p15.2
LOCUSID
ALIAS
CCT-epsilon,CCTE,HEL-S-69,PNAS-102,TCP-1-epsilon
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 22948
MIM: 610150
HGNC: 1618
Ensembl: ENSG00000150753
Variants:
dbSNP: 22948
ClinVar: 22948
TCGA: ENSG00000150753
COSMIC: CCT5
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 36768350 | 2023 | Structural and Dynamic Disturbances Revealed by Molecular Dynamics Simulations Predict the Impact on Function of CCT5 Chaperonin Mutations Associated with Rare Severe Distal Neuropathies. | 2 |
| 36768350 | 2023 | Structural and Dynamic Disturbances Revealed by Molecular Dynamics Simulations Predict the Impact on Function of CCT5 Chaperonin Mutations Associated with Rare Severe Distal Neuropathies. | 2 |
| 35194191 | 2022 | CCT5 induces epithelial-mesenchymal transition to promote gastric cancer lymph node metastasis by activating the Wnt/β-catenin signalling pathway. | 22 |
| 35194191 | 2022 | CCT5 induces epithelial-mesenchymal transition to promote gastric cancer lymph node metastasis by activating the Wnt/β-catenin signalling pathway. | 22 |
| 34217974 | 2021 | CCT5 interacts with cyclin D1 promoting lung adenocarcinoma cell migration and invasion. | 10 |
| 34217974 | 2021 | CCT5 interacts with cyclin D1 promoting lung adenocarcinoma cell migration and invasion. | 10 |
| 33076433 | 2020 | A Novel CCT5 Missense Variant Associated with Early Onset Motor Neuropathy. | 6 |
| 33076433 | 2020 | A Novel CCT5 Missense Variant Associated with Early Onset Motor Neuropathy. | 6 |
| 25995452 | 2015 | Structural Mechanisms of Mutant Huntingtin Aggregation Suppression by the Synthetic Chaperonin-like CCT5 Complex Explained by Cryoelectron Tomography. | 27 |
| 25995452 | 2015 | Structural Mechanisms of Mutant Huntingtin Aggregation Suppression by the Synthetic Chaperonin-like CCT5 Complex Explained by Cryoelectron Tomography. | 27 |
| 25124038 | 2014 | Biochemical characterization of mutants in chaperonin proteins CCT4 and CCT5 associated with hereditary sensory neuropathy. | 18 |
| 25124038 | 2014 | Biochemical characterization of mutants in chaperonin proteins CCT4 and CCT5 associated with hereditary sensory neuropathy. | 18 |
| 23612981 | 2013 | Human CCT4 and CCT5 chaperonin subunits expressed in Escherichia coli form biologically active homo-oligomers. | 38 |
| 23612981 | 2013 | Human CCT4 and CCT5 chaperonin subunits expressed in Escherichia coli form biologically active homo-oligomers. | 38 |
| 22232265 | 2012 | A novel function of the human chaperonin CCT epsilon subunit in yeast. | 1 |
Citation
Dessen P
CCT5 (chaperonin containing TCP1 subunit 5)
Atlas Genet Cytogenet Oncol Haematol. 2007-10-01
Online version: http://atlasgeneticsoncology.org/gene/49762/cct5
