CALCR (calcitonin receptor)

2007-10-01  

Identity

HGNC
CALCR
LOCATION
7q21.3
LOCUSID
799
ALIAS
CRT,CT-R,CTR,CTR1
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 799
MIM: 114131
HGNC: 1440
Ensembl: ENSG00000004948

Variants:

dbSNP: 799
ClinVar: 799
TCGA: ENSG00000004948
COSMIC: CALCR

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000004948ENST00000359558A0A0A0MRG0
ENSG00000004948ENST00000360249D8MIV0
ENSG00000004948ENST00000394441A0A0C4DG16
ENSG00000004948ENST00000415529P30988
ENSG00000004948ENST00000423724P30988
ENSG00000004948ENST00000426151A0A0C4DG16
ENSG00000004948ENST00000649521A0A0A0MSQ7

Expression (GTEx)

0
1
2
3
4
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
Neuroactive ligand-receptor interactionKEGGko04080
Neuroactive ligand-receptor interactionKEGGhsa04080
Osteoclast differentiationKEGGko04380
Osteoclast differentiationKEGGhsa04380
Signal TransductionREACTOMER-HSA-162582
Signaling by GPCRREACTOMER-HSA-372790
GPCR ligand bindingREACTOMER-HSA-500792
Class B/2 (Secretin family receptors)REACTOMER-HSA-373080
Calcitonin-like ligand receptorsREACTOMER-HSA-419812
GPCR downstream signalingREACTOMER-HSA-388396
G alpha (s) signalling eventsREACTOMER-HSA-418555

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
hypothalamus
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
368347802023Polymorphisms in Genes Encoding VDR, CALCR and Antioxidant Enzymes as Predictors of Bone Tissue Condition in Young, Healthy Men.2
375434792023Calcitonin/PAC(1) receptor splice variants: a blind spot in migraine research.0
368347802023Polymorphisms in Genes Encoding VDR, CALCR and Antioxidant Enzymes as Predictors of Bone Tissue Condition in Young, Healthy Men.2
375434792023Calcitonin/PAC(1) receptor splice variants: a blind spot in migraine research.0
350908912022Copper(II) import and reduction are dependent on His-Met clusters in the extracellular amino terminus of human copper transporter-1.5
352026092022Dynamical interplay between the human high-affinity copper transporter hCtr1 and its cognate metal ion.3
360885852022Association of TRPV5, CASR, and CALCR genetic variants with kidney stone disease susceptibility in Egyptians through main effects and gene-gene interactions.2
350908912022Copper(II) import and reduction are dependent on His-Met clusters in the extracellular amino terminus of human copper transporter-1.5
352026092022Dynamical interplay between the human high-affinity copper transporter hCtr1 and its cognate metal ion.3
360885852022Association of TRPV5, CASR, and CALCR genetic variants with kidney stone disease susceptibility in Egyptians through main effects and gene-gene interactions.2
338235672021Gender-Dependent Reference Range of Serum Calcitonin Levels in Healthy Korean Adults.3
343127712021Genetic Depletion of Amylin/Calcitonin Receptors Improves Memory and Learning in Transgenic Alzheimer's Disease Mouse Models.6
344178122021CALCR knockdown inhibits the development and progression of non-small-cell lung cancer.1
338235672021Gender-Dependent Reference Range of Serum Calcitonin Levels in Healthy Korean Adults.3
343127712021Genetic Depletion of Amylin/Calcitonin Receptors Improves Memory and Learning in Transgenic Alzheimer's Disease Mouse Models.6

Citation

Dessen P

CALCR (calcitonin receptor)

Atlas Genet Cytogenet Oncol Haematol. 2007-10-01

Online version: http://atlasgeneticsoncology.org/gene/49768/tumors-explorer/haematological-explorer/gene-fusions/?id=49768