SOD3 (superoxide dismutase 3)

2007-10-01  

Identity

HGNC
SOD3
LOCATION
4p15.2
LOCUSID
6649
ALIAS
EC-SOD

Other Information

Locus ID:

NCBI: 6649
MIM: 185490
HGNC: 11181
Ensembl: ENSG00000109610

Variants:

dbSNP: 6649
ClinVar: 6649
TCGA: ENSG00000109610
COSMIC: SOD3

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000109610ENST00000382120P08294
ENSG00000109610ENST00000382120A0A140VJU8
ENSG00000109610ENST00000598411M0R1V4

Expression (GTEx)

0
500
1000
1500
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
Cellular responses to stressREACTOMER-HSA-2262752
Detoxification of Reactive Oxygen SpeciesREACTOMER-HSA-3299685

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
379923012024Deciphering MMP9's dual role in regulating SOD3 through protein-protein interactions.0
381418892024SOD3 regulates FLT1 to affect bone metabolism by promoting osteogenesis and inhibiting adipogenesis through PI3K/AKT and MAPK pathways.0
379923012024Deciphering MMP9's dual role in regulating SOD3 through protein-protein interactions.0
381418892024SOD3 regulates FLT1 to affect bone metabolism by promoting osteogenesis and inhibiting adipogenesis through PI3K/AKT and MAPK pathways.0
366066882023Core Fucosylation Is Required for the Secretion of and the Enzymatic Activity of SOD3 in Nonsmall-Cell Lung Cancer Cells.2
366066882023Core Fucosylation Is Required for the Secretion of and the Enzymatic Activity of SOD3 in Nonsmall-Cell Lung Cancer Cells.2
347589472022Effects of SNPs in SOD2 and SOD3 interacted with fluoride exposure on the susceptibility of dental fluorosis.2
352660532022Superoxide dismutase isozymes in cerebral organoids from autism spectrum disorder patients.1
352717792022Combined action of FOXO1 and superoxide dismutase 3 promotes MDA-MB-231 cell migration.2
353125912022Decreased Expression of EC-SOD and Fibulin-5 in Alveolar Walls of Lungs From COPD Patients.1
347589472022Effects of SNPs in SOD2 and SOD3 interacted with fluoride exposure on the susceptibility of dental fluorosis.2
352660532022Superoxide dismutase isozymes in cerebral organoids from autism spectrum disorder patients.1
352717792022Combined action of FOXO1 and superoxide dismutase 3 promotes MDA-MB-231 cell migration.2
353125912022Decreased Expression of EC-SOD and Fibulin-5 in Alveolar Walls of Lungs From COPD Patients.1
321565182021Study of the association between SOD3G362A polymorphism, seminal SOD activity and risk for idiopathic male infertility in Algeria.1

Citation

Dessen P

SOD3 (superoxide dismutase 3)

Atlas Genet Cytogenet Oncol Haematol. 2007-10-01

Online version: http://atlasgeneticsoncology.org/gene/49773