FUT4 (fucosyltransferase 4)

2007-11-01  

Identity

HGNC
LOCATION
11q21
LOCUSID
ALIAS
CD15,ELFT,FCT3A,FUC-TIV,FUTIV,LeX,SSEA-1

Other Information

Locus ID:

NCBI: 2526
MIM: 104230
HGNC: 4015
Ensembl: ENSG00000196371

Variants:

dbSNP: 2526
ClinVar: 2526
TCGA: ENSG00000196371
COSMIC: FUT4

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000196371ENST00000358752P22083

Expression (GTEx)

0
1
2
3
4
5
6
7
8
9

Pathways

PathwaySourceExternal ID
Glycosphingolipid biosynthesis - lacto and neolacto seriesKEGGko00601
Glycosphingolipid biosynthesis - lacto and neolacto seriesKEGGhsa00601
Metabolic pathwaysKEGGhsa01100
Mannose type O-glycan biosynthesisKEGGko00515
Mannose type O-glycan biosynthesisKEGGhsa00515

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
379634322024CD15 Is a Risk Predictor and a Novel Target in Clear Cell Renal Cell Carcinoma.0
383430562024Silencing FUT4 Inhibits the Progression of Osteosarcoma through Activation of FOXO1.0
379634322024CD15 Is a Risk Predictor and a Novel Target in Clear Cell Renal Cell Carcinoma.0
383430562024Silencing FUT4 Inhibits the Progression of Osteosarcoma through Activation of FOXO1.0
369327482023X-ray inhibits FUT4-mediated proliferation in A549 cells by downregulating SP1 expression.0
370746232023ST3GalIV drives SLeX biosynthesis in gastrointestinal cancer cells and associates with cancer cell motility.1
369327482023X-ray inhibits FUT4-mediated proliferation in A549 cells by downregulating SP1 expression.0
370746232023ST3GalIV drives SLeX biosynthesis in gastrointestinal cancer cells and associates with cancer cell motility.1
323422762022SMYD2 facilitates cancer cell malignancy and xenograft tumor development through ERBB2-mediated FUT4 expression in colon cancer.7
349697562022CD15(+) Bone Marrow-derived Cells Are Regulators of Immune Response in ARG1-producing Colorectal Cancer Cells.0
323422762022SMYD2 facilitates cancer cell malignancy and xenograft tumor development through ERBB2-mediated FUT4 expression in colon cancer.7
349697562022CD15(+) Bone Marrow-derived Cells Are Regulators of Immune Response in ARG1-producing Colorectal Cancer Cells.0
334414042021Specific Norovirus Interaction with Lewis x and Lewis a on Human Intestinal Inflammatory Mucosa during Refractory Inflammatory Bowel Disease.5
335456302021CD15 immunostaining improves placental diagnosis of fetal hypoxia.3
334414042021Specific Norovirus Interaction with Lewis x and Lewis a on Human Intestinal Inflammatory Mucosa during Refractory Inflammatory Bowel Disease.5

Citation

Dessen P

FUT4 (fucosyltransferase 4)

Atlas Genet Cytogenet Oncol Haematol. 2007-11-01

Online version: http://atlasgeneticsoncology.org/gene/49792/fut4