SOX5 (SRY-box transcription factor 5)

2007-11-01  

Identity

HGNC
SOX5
LOCATION
12p12.1
LOCUSID
6660
ALIAS
L-SOX5,L-SOX5B,L-SOX5F,LAMSHF
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 6660
MIM: 604975
HGNC: 11201
Ensembl: ENSG00000134532

Variants:

dbSNP: 6660
ClinVar: 6660
TCGA: ENSG00000134532
COSMIC: SOX5

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000134532ENST00000367206I3L0A5
ENSG00000134532ENST00000381381P35711
ENSG00000134532ENST00000396007P35711
ENSG00000134532ENST00000441133G3V0H1
ENSG00000134532ENST00000446891A0A2R8Y5Q1
ENSG00000134532ENST00000451604P35711
ENSG00000134532ENST00000451604A0A024RB06
ENSG00000134532ENST00000536729A0A2R8Y7P3
ENSG00000134532ENST00000537393F5H0I3
ENSG00000134532ENST00000538083F5GWL1
ENSG00000134532ENST00000541847F5H876
ENSG00000134532ENST00000545921P35711
ENSG00000134532ENST00000646273P35711
ENSG00000134532ENST00000659413A0A590UJ80

Expression (GTEx)

0
5
10
15
20
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

References

Pubmed IDYearTitleCitations
359756392023circ-LDLRAD3 Knockdown Reduces Cisplatin Chemoresistance and Inhibits the Development of Gastric Cancer with Cisplatin Resistance through miR-588 Enrichment-Mediated SOX5 Inhibition.6
377023212023Lamb-Shaffer syndrome: 20 Spanish patients and literature review expands the view of neurodevelopmental disorders caused by SOX5 haploinsufficiency.2
378621522023EGR1/LINC00839/SOX5 axis modulates migration, invasion and Gemcitabine resistance of bladder cancer cells.2
359756392023circ-LDLRAD3 Knockdown Reduces Cisplatin Chemoresistance and Inhibits the Development of Gastric Cancer with Cisplatin Resistance through miR-588 Enrichment-Mediated SOX5 Inhibition.6
377023212023Lamb-Shaffer syndrome: 20 Spanish patients and literature review expands the view of neurodevelopmental disorders caused by SOX5 haploinsufficiency.2
378621522023EGR1/LINC00839/SOX5 axis modulates migration, invasion and Gemcitabine resistance of bladder cancer cells.2
350896592022LINC00520 up-regulates SOX5 to promote cell proliferation and invasion by miR-4516 in human hepatocellular carcinoma.5
358805682022SOX5 promotes cell growth and migration through modulating the DNMT1/p21 pathway in bladder cancer.3
350896592022LINC00520 up-regulates SOX5 to promote cell proliferation and invasion by miR-4516 in human hepatocellular carcinoma.5
358805682022SOX5 promotes cell growth and migration through modulating the DNMT1/p21 pathway in bladder cancer.3
329603572021miR-23a-3p regulated by LncRNA SNHG5 suppresses the chondrogenic differentiation of human adipose-derived stem cells via targeting SOX6/SOX5.6
331769662021Serum levels of miRNA-21-5p in vitiligo patients and effects of miRNA-21-5p on SOX5, beta-catenin, CDK2 and MITF protein expression in normal human melanocytes.14
332961432021Clinical spectrum and follow-up in six individuals with Lamb-Shaffer syndrome (SOX5).3
338244202021LncRNA UCC promotes epithelial-mesenchymal transition via the miR-143-3p/SOX5 axis in non-small-cell lung cancer.10
329603572021miR-23a-3p regulated by LncRNA SNHG5 suppresses the chondrogenic differentiation of human adipose-derived stem cells via targeting SOX6/SOX5.6

Citation

Dessen P

SOX5 (SRY-box transcription factor 5)

Atlas Genet Cytogenet Oncol Haematol. 2007-11-01

Online version: http://atlasgeneticsoncology.org/gene/49803/js/lib/case-report-explorer/gene-fusions-explorer/