Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 3483
MIM: 601489
HGNC: 5468
Ensembl: ENSG00000099769
Variants:
dbSNP: 3483
ClinVar: 3483
TCGA: ENSG00000099769
COSMIC: IGFALS
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000099769 | ENST00000215539 | P35858 |
| ENSG00000099769 | ENST00000415638 | P35858 |
| ENSG00000099769 | ENST00000568221 | H3BSX8 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 33664485 | 2021 | Virus-inducible IGFALS facilitates innate immune responses by mediating IRAK1 and TRAF6 activation. | 3 |
| 34238413 | 2021 | [Liver Tissue-specific Genes IGFALS,CYP3A4,SLC22A1 and CYP2E1 May be Associated with Poor Prognosis of Liver Cancer]. | 1 |
| 33664485 | 2021 | Virus-inducible IGFALS facilitates innate immune responses by mediating IRAK1 and TRAF6 activation. | 3 |
| 34238413 | 2021 | [Liver Tissue-specific Genes IGFALS,CYP3A4,SLC22A1 and CYP2E1 May be Associated with Poor Prognosis of Liver Cancer]. | 1 |
| 31834863 | 2020 | Pathogenic/likely pathogenic variants in the SHOX, GHR and IGFALS genes among Indian children with idiopathic short stature. | 11 |
| 31834863 | 2020 | Pathogenic/likely pathogenic variants in the SHOX, GHR and IGFALS genes among Indian children with idiopathic short stature. | 11 |
| 28249955 | 2017 | Clinical and biochemical characteristics and bone mineral density of homozygous, compound heterozygous and heterozygous carriers of three novel IGFALS mutations. | 9 |
| 28389567 | 2017 | Large-scale analysis of variation in the insulin-like growth factor family in humans reveals rare disease links and common polymorphisms. | 14 |
| 28249955 | 2017 | Clinical and biochemical characteristics and bone mineral density of homozygous, compound heterozygous and heterozygous carriers of three novel IGFALS mutations. | 9 |
| 28389567 | 2017 | Large-scale analysis of variation in the insulin-like growth factor family in humans reveals rare disease links and common polymorphisms. | 14 |
| 27018247 | 2016 | Assessment of pathogenicity of natural IGFALS gene variants by in silico bioinformatics tools and in vitro functional studies. | 3 |
| 27018247 | 2016 | Assessment of pathogenicity of natural IGFALS gene variants by in silico bioinformatics tools and in vitro functional studies. | 3 |
| 26704943 | 2015 | [Structure and function of insulin-like growth factor acid-labile subunits in mammalian homologues]. | 2 |
| 26704943 | 2015 | [Structure and function of insulin-like growth factor acid-labile subunits in mammalian homologues]. | 2 |
| 24423360 | 2014 | IGFALS gene dosage effects on serum IGF-I and glucose metabolism, body composition, bone growth in length and width, and the pharmacokinetics of recombinant human IGF-I administration. | 9 |
Citation
Dessen P
IGFALS (insulin like growth factor binding protein acid labile subunit)
Atlas Genet Cytogenet Oncol Haematol. 2007-11-01
Online version: http://atlasgeneticsoncology.org/gene/49824/igfals
