Identity
HGNC
LOCATION
1p36.33
LOCUSID
ALIAS
AGRIN,CMS8,CMSPPD
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 375790
MIM: 103320
HGNC: 329
Ensembl: ENSG00000188157
Variants:
dbSNP: 375790
ClinVar: 375790
TCGA: ENSG00000188157
COSMIC: AGRN
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000188157 | ENST00000379370 | O00468 |
| ENSG00000188157 | ENST00000620552 | A0A087X208 |
| ENSG00000188157 | ENST00000651234 | A0A494C1I6 |
| ENSG00000188157 | ENST00000652369 | A0A494C0G5 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 36609795 | 2023 | Genes encoding agrin (AGRN) and neurotrypsin (PRSS12) are associated with muscle mass, strength and plasma C-terminal agrin fragment concentration. | 4 |
| 37321467 | 2023 | AGRN promotes lung adenocarcinoma progression by activating Notch signaling pathway and acts as a therapeutic target. | 2 |
| 37356721 | 2023 | The collagen ColQ binds to LRP4 and regulates the activation of the Muscle-Specific Kinase-LRP4 receptor complex by agrin at the neuromuscular junction. | 1 |
| 37562951 | 2023 | Association between the 110-kDa C-terminal agrin fragment and skeletal muscle decline among community-dwelling older women. | 1 |
| 37841281 | 2023 | Bioinformatics-based analysis of the roles of basement membrane-related gene AGRN in systemic lupus erythematosus and pan-cancer development. | 0 |
| 36609795 | 2023 | Genes encoding agrin (AGRN) and neurotrypsin (PRSS12) are associated with muscle mass, strength and plasma C-terminal agrin fragment concentration. | 4 |
| 37321467 | 2023 | AGRN promotes lung adenocarcinoma progression by activating Notch signaling pathway and acts as a therapeutic target. | 2 |
| 37356721 | 2023 | The collagen ColQ binds to LRP4 and regulates the activation of the Muscle-Specific Kinase-LRP4 receptor complex by agrin at the neuromuscular junction. | 1 |
| 37562951 | 2023 | Association between the 110-kDa C-terminal agrin fragment and skeletal muscle decline among community-dwelling older women. | 1 |
| 37841281 | 2023 | Bioinformatics-based analysis of the roles of basement membrane-related gene AGRN in systemic lupus erythematosus and pan-cancer development. | 0 |
| 34400559 | 2022 | Myasthenia gravis genome-wide association study implicates AGRN as a risk locus. | 3 |
| 34920013 | 2022 | Association between frailty and C-terminal agrin fragment with 3-month mortality following ST-elevation myocardial infarction. | 4 |
| 35948834 | 2022 | Severe congenital myasthenic syndromes caused by agrin mutations affecting secretion by motoneurons. | 3 |
| 36233091 | 2022 | Neuronal Agrin Promotes Proliferation of Primary Human Myoblasts in an Age-Dependent Manner. | 5 |
| 34400559 | 2022 | Myasthenia gravis genome-wide association study implicates AGRN as a risk locus. | 3 |
Citation
Dessen P
AGRN (agrin)
Atlas Genet Cytogenet Oncol Haematol. 2007-12-01
Online version: http://atlasgeneticsoncology.org/gene/49849/agrn
