Identity
HGNC
LOCATION
20p12.1
LOCUSID
ALIAS
ACTDP,ADF,HEL32,bA462D18.2
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 11034
MIM: 609114
HGNC: 15750
Ensembl: ENSG00000125868
Variants:
dbSNP: 11034
ClinVar: 11034
TCGA: ENSG00000125868
COSMIC: DSTN
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000125868 | ENST00000246069 | P60981 |
| ENSG00000125868 | ENST00000246069 | V9HWA6 |
| ENSG00000125868 | ENST00000449141 | F6RFD5 |
| ENSG00000125868 | ENST00000474024 | P60981 |
Expression (GTEx)
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 37019366 | 2023 | DSTN Hypomethylation Promotes Radiotherapy Resistance of Rectal Cancer by Activating the Wnt/β-Catenin Signaling Pathway. | 1 |
| 37019366 | 2023 | DSTN Hypomethylation Promotes Radiotherapy Resistance of Rectal Cancer by Activating the Wnt/β-Catenin Signaling Pathway. | 1 |
| 34120636 | 2021 | Positive natural selection of N6-methyladenosine on the RNAs of processed pseudogenes. | 9 |
| 34169836 | 2021 | ADF and cofilin-1 collaborate to promote cortical actin flow and the leader bleb-based migration of confined cells. | 12 |
| 34559579 | 2021 | The actin depolymerizing factor destrin serves as a negative feedback inhibitor of smooth muscle cell differentiation. | 2 |
| 34120636 | 2021 | Positive natural selection of N6-methyladenosine on the RNAs of processed pseudogenes. | 9 |
| 34169836 | 2021 | ADF and cofilin-1 collaborate to promote cortical actin flow and the leader bleb-based migration of confined cells. | 12 |
| 34559579 | 2021 | The actin depolymerizing factor destrin serves as a negative feedback inhibitor of smooth muscle cell differentiation. | 2 |
| 32878967 | 2020 | Destrin Contributes to Lung Adenocarcinoma Progression by Activating Wnt/β-Catenin Signaling Pathway. | 12 |
| 32878967 | 2020 | Destrin Contributes to Lung Adenocarcinoma Progression by Activating Wnt/β-Catenin Signaling Pathway. | 12 |
| 26996939 | 2016 | TIRF microscopy analysis of human Cof1, Cof2, and ADF effects on actin filament severing and turnover. | 31 |
| 26996939 | 2016 | TIRF microscopy analysis of human Cof1, Cof2, and ADF effects on actin filament severing and turnover. | 31 |
| 22898637 | 2012 | The actin binding protein destrin is associated with growth and perineural invasion of pancreatic cancer. | 9 |
| 22898637 | 2012 | The actin binding protein destrin is associated with growth and perineural invasion of pancreatic cancer. | 9 |
| 21571222 | 2011 | ADF/cofilin regulates secretory cargo sorting at the TGN via the Ca2+ ATPase SPCA1. | 57 |
Citation
Dessen P
DSTN (destrin, actin depolymerizing factor)
Atlas Genet Cytogenet Oncol Haematol. 2007-12-01
Online version: http://atlasgeneticsoncology.org/gene/49860/dstn
