Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 3938
MIM: 603202
HGNC: 6530
Ensembl: ENSG00000115850
Variants:
dbSNP: 3938
ClinVar: 3938
TCGA: ENSG00000115850
COSMIC: LCT
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000115850 | ENST00000264162 | P09848 |
| ENSG00000115850 | ENST00000452974 | H0Y4E4 |
Expression (GTEx)
Pathways
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38253929 | 2024 | Variant of the lactase LCT gene explains association between milk intake and incident type 2 diabetes. | 1 |
| 38253929 | 2024 | Variant of the lactase LCT gene explains association between milk intake and incident type 2 diabetes. | 1 |
| 36604367 | 2023 | Milk intake, lactase persistence genotype, plasma proteins and risks of cardiovascular events in the Swedish general population. | 2 |
| 36695417 | 2023 | DNA polymorphisms associated with lactase persistence, self-perceived symptoms of lactose intolerance, milk and dairy consumption, and ancestry, in the Uruguayan population. | 0 |
| 37354976 | 2023 | Association of Estimated Daily Lactose Consumption, Lactase Persistence Genotype (rs4988235), and Gut Microbiota in Healthy Adults in the United States. | 0 |
| 36604367 | 2023 | Milk intake, lactase persistence genotype, plasma proteins and risks of cardiovascular events in the Swedish general population. | 2 |
| 36695417 | 2023 | DNA polymorphisms associated with lactase persistence, self-perceived symptoms of lactose intolerance, milk and dairy consumption, and ancestry, in the Uruguayan population. | 0 |
| 37354976 | 2023 | Association of Estimated Daily Lactose Consumption, Lactase Persistence Genotype (rs4988235), and Gut Microbiota in Healthy Adults in the United States. | 0 |
| 35007711 | 2022 | Hypomorphic variants of lactase-phlorizin hydrolase in congenital lactase deficiency are trafficking incompetent and functionally inactive. | 1 |
| 35115689 | 2022 | Combined effects of host genetics and diet on human gut microbiota and incident disease in a single population cohort. | 118 |
| 35115690 | 2022 | Effect of host genetics on the gut microbiome in 7,738 participants of the Dutch Microbiome Project. | 95 |
| 36129808 | 2022 | Very low frequency of the lactase persistence allele LCT-13910T in the Armenian population. | 0 |
| 36334882 | 2022 | Lactase persistence phenotype and genotype in Iranian Mazani-Shahmirzadi and Afghan Hazara ethnicities. | 0 |
| 35007711 | 2022 | Hypomorphic variants of lactase-phlorizin hydrolase in congenital lactase deficiency are trafficking incompetent and functionally inactive. | 1 |
| 35115689 | 2022 | Combined effects of host genetics and diet on human gut microbiota and incident disease in a single population cohort. | 118 |
Citation
Dessen P
LCT (lactase)
Atlas Genet Cytogenet Oncol Haematol. 2007-12-01
Online version: http://atlasgeneticsoncology.org/gene/49871/lct
