PROM2 (prominin 2)

2007-12-01  

Identity

HGNC
LOCATION
2q11.1
LOCUSID
ALIAS
PROML2
FUSION GENES

Other Information

Locus ID:

NCBI: 150696
MIM: 617160
HGNC: 20685
Ensembl: ENSG00000155066

Variants:

dbSNP: 150696
ClinVar: 150696
TCGA: ENSG00000155066
COSMIC: PROM2

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000155066ENST00000317620Q8N271
ENSG00000155066ENST00000317668Q8N271
ENSG00000155066ENST00000403131Q8N271
ENSG00000155066ENST00000431567F8WDW5

Expression (GTEx)

0
50
100
150

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
385152782024PROM2 overexpression induces metastatic potential through epithelial-to-mesenchymal transition and ferroptosis resistance in human cancers.2
385152782024PROM2 overexpression induces metastatic potential through epithelial-to-mesenchymal transition and ferroptosis resistance in human cancers.2
376657412023Prominin 2 decreases cisplatin sensitivity in non-small cell lung cancer and is modulated by CTCC binding factor.2
376657412023Prominin 2 decreases cisplatin sensitivity in non-small cell lung cancer and is modulated by CTCC binding factor.2
347286132021LncRNA RP11-89 facilitates tumorigenesis and ferroptosis resistance through PROM2-activated iron export by sponging miR-129-5p in bladder cancer.66
347286132021LncRNA RP11-89 facilitates tumorigenesis and ferroptosis resistance through PROM2-activated iron export by sponging miR-129-5p in bladder cancer.66
311647162020PROM1 and PROM2 expression differentially modulates clinical prognosis of cancer: a multiomics analysis.28
321232872020PROM2 promotes gemcitabine chemoresistance via activating the Akt signaling pathway in pancreatic cancer.11
311647162020PROM1 and PROM2 expression differentially modulates clinical prognosis of cancer: a multiomics analysis.28
321232872020PROM2 promotes gemcitabine chemoresistance via activating the Akt signaling pathway in pancreatic cancer.11
317356632019Prominin2 Drives Ferroptosis Resistance by Stimulating Iron Export.232
317356632019Prominin2 Drives Ferroptosis Resistance by Stimulating Iron Export.232
235833802013Prominin-2 expression increases protrusions, decreases caveolae and inhibits Cdc42 dependent fluid phase endocytosis.8
235833802013Prominin-2 expression increases protrusions, decreases caveolae and inhibits Cdc42 dependent fluid phase endocytosis.8
203333962010Prominin-2 is a novel marker of distal tubules and collecting ducts of the human and murine kidney.11

Citation

Dessen P

PROM2 (prominin 2)

Atlas Genet Cytogenet Oncol Haematol. 2007-12-01

Online version: http://atlasgeneticsoncology.org/gene/49882/prom2