Identity
HGNC
LOCATION
1p35.2
LOCUSID
ALIAS
ORXR1,OX1R,OXR1
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 3061
MIM: 602392
HGNC: 4848
Ensembl: ENSG00000121764
Variants:
dbSNP: 3061
ClinVar: 3061
TCGA: ENSG00000121764
COSMIC: HCRTR1
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000121764 | ENST00000373705 | A6NMV7 |
| ENSG00000121764 | ENST00000373706 | O43613 |
| ENSG00000121764 | ENST00000403528 | O43613 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 37572990 | 2024 | Orexin-A/OX1R is involved in regulation of autophagy to promote cortisol secretion in adrenocortical cell. | 0 |
| 37572990 | 2024 | Orexin-A/OX1R is involved in regulation of autophagy to promote cortisol secretion in adrenocortical cell. | 0 |
| 37054895 | 2023 | Internal and external modulation factors of the orexin system (REVIEW). | 3 |
| 37054895 | 2023 | Internal and external modulation factors of the orexin system (REVIEW). | 3 |
| 33212156 | 2021 | Orexin-A protects against cerebral ischemia-reperfusion injury by inhibiting excessive autophagy through OX1R-mediated MAPK/ERK/mTOR pathway. | 19 |
| 34439801 | 2021 | Identification and Characterization of Cannabidiol as an OX1R Antagonist by Computational and In Vitro Functional Validation. | 2 |
| 34472713 | 2021 | Human adipose tissue is a putative direct target of daytime orexin with favorable metabolic effects: A cross-sectional study. | 1 |
| 33212156 | 2021 | Orexin-A protects against cerebral ischemia-reperfusion injury by inhibiting excessive autophagy through OX1R-mediated MAPK/ERK/mTOR pathway. | 19 |
| 34439801 | 2021 | Identification and Characterization of Cannabidiol as an OX1R Antagonist by Computational and In Vitro Functional Validation. | 2 |
| 34472713 | 2021 | Human adipose tissue is a putative direct target of daytime orexin with favorable metabolic effects: A cross-sectional study. | 1 |
| 31668922 | 2020 | Transmembrane peptide 4 and 5 of APJ are essential for its heterodimerization with OX1R. | 2 |
| 31983458 | 2020 | Orexin A associates with inflammation by interacting with OX1R/OX2R receptor and activating prepro-Orexin in cancer tissues of gastric cancer patients. | 4 |
| 32652147 | 2020 | Association of orexin/hypocretin receptor gene (HCRTR1) with reward sensitivity, and interaction with gender. | 3 |
| 31668922 | 2020 | Transmembrane peptide 4 and 5 of APJ are essential for its heterodimerization with OX1R. | 2 |
| 31983458 | 2020 | Orexin A associates with inflammation by interacting with OX1R/OX2R receptor and activating prepro-Orexin in cancer tissues of gastric cancer patients. | 4 |
Citation
Dessen P
HCRTR1 (hypocretin receptor 1)
Atlas Genet Cytogenet Oncol Haematol. 2007-12-01
Online version: http://atlasgeneticsoncology.org/gene/49911/hcrtr1
