MAPK15 (mitogen-activated protein kinase 15)

2007-12-01  

Identity

HGNC
LOCATION
8q24.3
LOCUSID
ALIAS
ERK7,ERK8
FUSION GENES

Other Information

Locus ID:

NCBI: 225689
MIM: 618616
HGNC: 24667
Ensembl: ENSG00000181085

Variants:

dbSNP: 225689
ClinVar: 225689
TCGA: ENSG00000181085
COSMIC: MAPK15

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000181085ENST00000338033Q8TD08
ENSG00000181085ENST00000395107Q8TD08
ENSG00000181085ENST00000395108Q8TD08

Expression (GTEx)

0
5
10
15
20
25
30
35
40
45

Pathways

PathwaySourceExternal ID
IL-17 signaling pathwayKEGGko04657
IL-17 signaling pathwayKEGGhsa04657

References

Pubmed IDYearTitleCitations
385557112024MAPK15 controls cellular responses to oxidative stress by regulating NRF2 activity and expression of its downstream target genes.0
385557112024MAPK15 controls cellular responses to oxidative stress by regulating NRF2 activity and expression of its downstream target genes.0
382032802023Mitogen-Activated Protein Kinase 15 Is a New Predictive Biomarker and Potential Therapeutic Target for Ovarian Cancer.1
382032802023Mitogen-Activated Protein Kinase 15 Is a New Predictive Biomarker and Potential Therapeutic Target for Ovarian Cancer.1
356427242022MAPK15 protects from oxidative stress-dependent cellular senescence by inducing the mitophagic process.7
356427242022MAPK15 protects from oxidative stress-dependent cellular senescence by inducing the mitophagic process.7
342248142021MAPK15-ULK1 signaling regulates mitophagy of airway epithelial cell in chronic obstructive pulmonary disease.11
342248142021MAPK15-ULK1 signaling regulates mitophagy of airway epithelial cell in chronic obstructive pulmonary disease.11
300706992018Regulation of human mitogen-activated protein kinase 15 (extracellular signal-regulated kinase 7/8) and its functions: A recent update.15
301313412018MAPK15 is part of the ULK complex and controls its activity to regulate early phases of the autophagic process.11
300706992018Regulation of human mitogen-activated protein kinase 15 (extracellular signal-regulated kinase 7/8) and its functions: A recent update.15
301313412018MAPK15 is part of the ULK complex and controls its activity to regulate early phases of the autophagic process.11
290212802017Primary Cilium Formation and Ciliary Protein Trafficking Is Regulated by the Atypical MAP Kinase MAPK15 in Caenorhabditis elegans and Human Cells.17
290212802017Primary Cilium Formation and Ciliary Protein Trafficking Is Regulated by the Atypical MAP Kinase MAPK15 in Caenorhabditis elegans and Human Cells.17
265955262016ERK8 is a novel HuR kinase that regulates tumour suppressor PDCD4 through a miR-21 dependent mechanism.13

Citation

Dessen P

MAPK15 (mitogen-activated protein kinase 15)

Atlas Genet Cytogenet Oncol Haematol. 2007-12-01

Online version: http://atlasgeneticsoncology.org/gene/49928/mapk15