Identity
HGNC
LOCATION
7q21.11
LOCUSID
ALIAS
ACVRIP1,AIP-1,AIP1,ARIP1,MAGI-2,NPHS15,SSCAM
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 9863
MIM: 606382
HGNC: 18957
Ensembl: ENSG00000187391
Variants:
dbSNP: 9863
ClinVar: 9863
TCGA: ENSG00000187391
COSMIC: MAGI2
RNA/Proteins
Expression (GTEx)
Pathways
| Pathway | Source | External ID |
|---|---|---|
| Rap1 signaling pathway | KEGG | hsa04015 |
| Rap1 signaling pathway | KEGG | ko04015 |
| Cell-Cell communication | REACTOME | R-HSA-1500931 |
| Nephrin interactions | REACTOME | R-HSA-373753 |
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 37358745 | 2024 | LncRNA MAGI2-AS3-Encoded Polypeptide Restrains the Proliferation and Migration of Breast Cancer Cells. | 2 |
| 37358745 | 2024 | LncRNA MAGI2-AS3-Encoded Polypeptide Restrains the Proliferation and Migration of Breast Cancer Cells. | 2 |
| 37950637 | 2023 | MAGI2 ameliorates podocyte apoptosis of diabetic kidney disease through communication with TGF-β-Smad3/nephrin pathway. | 0 |
| 37950637 | 2023 | MAGI2 ameliorates podocyte apoptosis of diabetic kidney disease through communication with TGF-β-Smad3/nephrin pathway. | 0 |
| 35294925 | 2022 | The TLR4/NF-κB/MAGI-2 signaling pathway mediates postoperative delirium. | 1 |
| 35294925 | 2022 | The TLR4/NF-κB/MAGI-2 signaling pathway mediates postoperative delirium. | 1 |
| 32730644 | 2021 | MAGI2-AS3 inhibits breast cancer by downregulating DNA methylation of MAGI2. | 24 |
| 33323781 | 2021 | Polymorphism in the MAGI2 Gene Modifies the Effect of Amyloid β on Neurodegeneration. | 2 |
| 33713943 | 2021 | Comparative study of immunohistochemical expression of ERG and MAGI2 in prostatic carcinoma. | 4 |
| 33761624 | 2021 | Novel insights for lncRNA MAGI2-AS3 in solid tumors. | 9 |
| 34237299 | 2021 | GLIDR promotes the progression of glioma by regulating the miR-4677-3p/MAGI2 axis. | 3 |
| 34375487 | 2021 | Genetic variants of SDCCAG8 and MAGI2 in mitosis-related pathway genes are independent predictors of cutaneous melanoma-specific survival. | 1 |
| 32730644 | 2021 | MAGI2-AS3 inhibits breast cancer by downregulating DNA methylation of MAGI2. | 24 |
| 33323781 | 2021 | Polymorphism in the MAGI2 Gene Modifies the Effect of Amyloid β on Neurodegeneration. | 2 |
| 33713943 | 2021 | Comparative study of immunohistochemical expression of ERG and MAGI2 in prostatic carcinoma. | 4 |
Citation
Dessen P
MAGI2 (membrane associated guanylate kinase, WW and PDZ domain containing 2)
Atlas Genet Cytogenet Oncol Haematol. 2007-12-01
Online version: http://atlasgeneticsoncology.org/gene/49960/magi2
