Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 9587
MIM: 618136
HGNC: 21059
Ensembl: ENSG00000124688
Variants:
dbSNP: 9587
ClinVar: 9587
TCGA: ENSG00000124688
COSMIC: MAD2L1BP
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000124688 | ENST00000372171 | Q15013 |
| ENSG00000124688 | ENST00000451025 | Q15013 |
Expression (GTEx)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 37334967 | 2023 | Biallelic variants in MAD2L1BP (p31(comet)) cause female infertility characterized by oocyte maturation arrest. | 1 |
| 37796616 | 2023 | Biallelic MAD2L1BP (p31comet) mutation is associated with mosaic aneuploidy and juvenile granulosa cell tumors. | 1 |
| 37334967 | 2023 | Biallelic variants in MAD2L1BP (p31(comet)) cause female infertility characterized by oocyte maturation arrest. | 1 |
| 37796616 | 2023 | Biallelic MAD2L1BP (p31comet) mutation is associated with mosaic aneuploidy and juvenile granulosa cell tumors. | 1 |
| 32029899 | 2020 | Mitotic slippage is determined by p31(comet) and the weakening of the spindle-assembly checkpoint. | 18 |
| 33051298 | 2020 | p31(comet) promotes homologous recombination by inactivating REV7 through the TRIP13 ATPase. | 18 |
| 32029899 | 2020 | Mitotic slippage is determined by p31(comet) and the weakening of the spindle-assembly checkpoint. | 18 |
| 33051298 | 2020 | p31(comet) promotes homologous recombination by inactivating REV7 through the TRIP13 ATPase. | 18 |
| 31118282 | 2019 | Role of Polo-like kinase 1 in the regulation of the action of p31(comet) in the disassembly of mitotic checkpoint complexes. | 9 |
| 31118282 | 2019 | Role of Polo-like kinase 1 in the regulation of the action of p31(comet) in the disassembly of mitotic checkpoint complexes. | 9 |
| 29408509 | 2018 | MAD2-p31(comet) axis deficiency reduces cell proliferation, migration and sensitivity of microtubule-interfering agents in glioma. | 4 |
| 29408509 | 2018 | MAD2-p31(comet) axis deficiency reduces cell proliferation, migration and sensitivity of microtubule-interfering agents in glioma. | 4 |
| 28659378 | 2017 | The AAA+ ATPase TRIP13 remodels HORMA domains through N-terminal engagement and unfolding. | 45 |
| 29208896 | 2017 | Mechanistic insight into TRIP13-catalyzed Mad2 structural transition and spindle checkpoint silencing. | 21 |
| 28659378 | 2017 | The AAA+ ATPase TRIP13 remodels HORMA domains through N-terminal engagement and unfolding. | 45 |
Citation
Dessen P
MAD2L1BP (MAD2L1 binding protein)
Atlas Genet Cytogenet Oncol Haematol. 2007-12-01
Online version: http://atlasgeneticsoncology.org/gene/49962/mad2l1bp
