SLC26A2 (solute carrier family 26 member 2)

2008-01-01  

Identity

HGNC
LOCATION
5q32
LOCUSID
ALIAS
D5S1708,DTD,DTDST,EDM4,MST153,MSTP157
FUSION GENES

Other Information

Locus ID:

NCBI: 1836
MIM: 606718
HGNC: 10994
Ensembl: ENSG00000155850

Variants:

dbSNP: 1836
ClinVar: 1836
TCGA: ENSG00000155850
COSMIC: SLC26A2

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000155850ENST00000286298P50443
ENSG00000155850ENST00000433184C9JAN6
ENSG00000155850ENST00000503336H0YA38

Expression (GTEx)

0
10
20
30
40
50
60
70

Pathways

PathwaySourceExternal ID
Transmembrane transport of small moleculesREACTOMER-HSA-382551
SLC-mediated transmembrane transportREACTOMER-HSA-425407
Transport of inorganic cations/anions and amino acids/oligopeptidesREACTOMER-HSA-425393
Multifunctional anion exchangersREACTOMER-HSA-427601
MetabolismREACTOMER-HSA-1430728
Metabolism of carbohydratesREACTOMER-HSA-71387
Glycosaminoglycan metabolismREACTOMER-HSA-1630316
Transport and synthesis of PAPSREACTOMER-HSA-174362
Biological oxidationsREACTOMER-HSA-211859
Phase II conjugationREACTOMER-HSA-156580
Cytosolic sulfonation of small moleculesREACTOMER-HSA-156584

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
389566002024Biallelic variants in SLC26A2 cause multiple epiphyseal dysplasia-4 by disturbing chondrocyte homeostasis.0
389566002024Biallelic variants in SLC26A2 cause multiple epiphyseal dysplasia-4 by disturbing chondrocyte homeostasis.0
360078412022Computational biology insights into genotype-clinical phenotype-protein phenotype relationships between novel SLC26A2 variants identified in inherited skeletal dysplasias.1
361406802022Clinical and Genetic Characteristics of Multiple Epiphyseal Dysplasia Type 4.2
360078412022Computational biology insights into genotype-clinical phenotype-protein phenotype relationships between novel SLC26A2 variants identified in inherited skeletal dysplasias.1
361406802022Clinical and Genetic Characteristics of Multiple Epiphyseal Dysplasia Type 4.2
318804112020Two unrelated pedigrees with achondrogenesis type 1b carrying a Japan-specific pathogenic variant in SLC26A2.1
318804112020Two unrelated pedigrees with achondrogenesis type 1b carrying a Japan-specific pathogenic variant in SLC26A2.1
304234442019Recessive multiple epiphyseal dysplasia - Clinical characteristics caused by rare compound heterozygous SLC26A2 genotypes.8
304625202019Role of N-glycosylation in the expression of human SLC26A2 and A3 anion transport membrane glycoproteins (1).1
304234442019Recessive multiple epiphyseal dysplasia - Clinical characteristics caused by rare compound heterozygous SLC26A2 genotypes.8
304625202019Role of N-glycosylation in the expression of human SLC26A2 and A3 anion transport membrane glycoproteins (1).1
290248312018Multiple SLC26A2 mutations occurring in a three-generational family.6
297241732018Dual novel mutations in SLC26A2 in two siblings with multiple epiphyseal dysplasia 4 from a Chinese family: a case report.3
290248312018Multiple SLC26A2 mutations occurring in a three-generational family.6

Citation

Dessen P

SLC26A2 (solute carrier family 26 member 2)

Atlas Genet Cytogenet Oncol Haematol. 2008-01-01

Online version: http://atlasgeneticsoncology.org/gene/49972/slc26a2