Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 54742
MIM: 615093
HGNC: 24225
Ensembl: ENSG00000160886
Variants:
dbSNP: 54742
ClinVar: 54742
TCGA: ENSG00000160886
COSMIC: LY6K
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000160886 | ENST00000292430 | Q17RY6 |
| ENSG00000160886 | ENST00000518841 | E5RGJ8 |
| ENSG00000160886 | ENST00000519387 | Q17RY6 |
| ENSG00000160886 | ENST00000522591 | H0YB07 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 36805500 | 2023 | Lymphocyte antigen 6K signaling to aurora kinase promotes advancement of the cell cycle and the growth of cancer cells, which is inhibited by LY6K-NSC243928 interaction. | 2 |
| 37076981 | 2023 | LY6K depletion modulates TGF-β and EGF signaling. | 2 |
| 36805500 | 2023 | Lymphocyte antigen 6K signaling to aurora kinase promotes advancement of the cell cycle and the growth of cancer cells, which is inhibited by LY6K-NSC243928 interaction. | 2 |
| 37076981 | 2023 | LY6K depletion modulates TGF-β and EGF signaling. | 2 |
| 34980214 | 2022 | Down-regulation of ZNF252P-AS1 alleviates ovarian cancer progression by binding miR-324-3p to downregulate LY6K. | 6 |
| 34980214 | 2022 | Down-regulation of ZNF252P-AS1 alleviates ovarian cancer progression by binding miR-324-3p to downregulate LY6K. | 6 |
| 33674747 | 2021 | LY6K-AS lncRNA is a lung adenocarcinoma prognostic biomarker and regulator of mitotic progression. | 14 |
| 33674747 | 2021 | LY6K-AS lncRNA is a lung adenocarcinoma prognostic biomarker and regulator of mitotic progression. | 14 |
| 32055849 | 2020 | LY6K promotes glioblastoma tumorigenicity via CAV-1-mediated ERK1/2 signaling enhancement. | 15 |
| 32055849 | 2020 | LY6K promotes glioblastoma tumorigenicity via CAV-1-mediated ERK1/2 signaling enhancement. | 15 |
| 30249107 | 2018 | MiRNA-500a-3p inhibits cell proliferation and invasion by targeting lymphocyte antigen 6 complex locus K (LY6K) in human non-small cell lung cancer. | 13 |
| 30249107 | 2018 | MiRNA-500a-3p inhibits cell proliferation and invasion by targeting lymphocyte antigen 6 complex locus K (LY6K) in human non-small cell lung cancer. | 13 |
| 27197181 | 2016 | Ly6E/K Signaling to TGFβ Promotes Breast Cancer Progression, Immune Escape, and Drug Resistance. | 59 |
| 27304060 | 2016 | miRNAs involved in LY6K and estrogen receptor α contribute to tamoxifen-susceptibility in breast cancer. | 16 |
| 27494879 | 2016 | Epigenetic activation of LY6K predicts the presence of metastasis and poor prognosis in breast carcinoma. | 9 |
Citation
Dessen P
LY6K (lymphocyte antigen 6 family member K)
Atlas Genet Cytogenet Oncol Haematol. 2008-01-01
Online version: http://atlasgeneticsoncology.org/gene/49996/ly6k
