YWHAZ (tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta)
2008-01-01 AffiliationIdentity
HGNC
LOCATION
8q22.3
LOCUSID
ALIAS
14-3-3-zeta,HEL-S-3,HEL-S-93,HEL4,KCIP-1,POPCHAS,YWHAD
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 7534
MIM: 601288
HGNC: 12855
Ensembl: ENSG00000164924
Variants:
dbSNP: 7534
ClinVar: 7534
TCGA: ENSG00000164924
COSMIC: YWHAZ
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38194803 | 2024 | CSF 14-3-3 zeta(ζ) isoform is associated with tau pathology and cognitive decline in Alzheimer's disease. | 0 |
| 38325743 | 2024 | 14-3-3 interaction with phosphodiesterase 8A sustains PKA signaling and downregulates the MAPK pathway. | 0 |
| 38341472 | 2024 | TMEM65 promotes gastric tumorigenesis by targeting YWHAZ to activate PI3K-Akt-mTOR pathway and is a therapeutic target. | 1 |
| 38674334 | 2024 | Structural Features and Physiological Associations of Human 14-3-3ζ Pseudogenes. | 0 |
| 38194803 | 2024 | CSF 14-3-3 zeta(ζ) isoform is associated with tau pathology and cognitive decline in Alzheimer's disease. | 0 |
| 38325743 | 2024 | 14-3-3 interaction with phosphodiesterase 8A sustains PKA signaling and downregulates the MAPK pathway. | 0 |
| 38341472 | 2024 | TMEM65 promotes gastric tumorigenesis by targeting YWHAZ to activate PI3K-Akt-mTOR pathway and is a therapeutic target. | 1 |
| 38674334 | 2024 | Structural Features and Physiological Associations of Human 14-3-3ζ Pseudogenes. | 0 |
| 36001342 | 2023 | YWHAZ variation causes intellectual disability and global developmental delay with brain malformation. | 5 |
| 36977605 | 2023 | Discovery of 14-3-3 zeta as a potential biomarker for cardiac hypertrophy. | 0 |
| 37224961 | 2023 | Molecular basis and dual ligand regulation of tetrameric estrogen receptor α/14-3-3ζ protein complex. | 2 |
| 37452033 | 2023 | High-throughput functional screen identifies YWHAZ as a key regulator of pancreatic cancer metastasis. | 1 |
| 36001342 | 2023 | YWHAZ variation causes intellectual disability and global developmental delay with brain malformation. | 5 |
| 36977605 | 2023 | Discovery of 14-3-3 zeta as a potential biomarker for cardiac hypertrophy. | 0 |
| 37224961 | 2023 | Molecular basis and dual ligand regulation of tetrameric estrogen receptor α/14-3-3ζ protein complex. | 2 |
Citation
Dessen P
YWHAZ (tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta)
Atlas Genet Cytogenet Oncol Haematol. 2008-01-01
Online version: http://atlasgeneticsoncology.org/gene/49997/ywhaz
