Identity
HGNC
LOCATION
11q22.3
LOCUSID
ALIAS
ACAT,MAT,T2,THIL
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 38
MIM: 607809
HGNC: 93
Ensembl: ENSG00000075239
Variants:
dbSNP: 38
ClinVar: 38
TCGA: ENSG00000075239
COSMIC: ACAT1
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38289172 | 2024 | Silencing lncRNA-DARS-AS1 suppresses nonsmall cell lung cancer progression by stimulating miR-302a-3p to inhibit ACAT1 expression. | 1 |
| 38684297 | 2024 | [Clinical analysis and genetic diagnosis of three children with Isoleucine metabolic disorders due to variants of HSD17B10 and ACAT1 genes]. | 0 |
| 38289172 | 2024 | Silencing lncRNA-DARS-AS1 suppresses nonsmall cell lung cancer progression by stimulating miR-302a-3p to inhibit ACAT1 expression. | 1 |
| 38684297 | 2024 | [Clinical analysis and genetic diagnosis of three children with Isoleucine metabolic disorders due to variants of HSD17B10 and ACAT1 genes]. | 0 |
| 36890220 | 2023 | ACAT1-mediated METTL3 acetylation inhibits cell migration and invasion in triple negative breast cancer. | 8 |
| 37185457 | 2023 | Elevated serum β-hydroxybutyrate, a circulating ketone metabolite, accelerates colorectal cancer proliferation and metastasis via ACAT1. | 4 |
| 36890220 | 2023 | ACAT1-mediated METTL3 acetylation inhibits cell migration and invasion in triple negative breast cancer. | 8 |
| 37185457 | 2023 | Elevated serum β-hydroxybutyrate, a circulating ketone metabolite, accelerates colorectal cancer proliferation and metastasis via ACAT1. | 4 |
| 34985712 | 2022 | Epigenetic inactivation of ACAT1 promotes epithelial-mesenchymal transition of clear cell renal cell carcinoma. | 4 |
| 36517760 | 2022 | Autophagy inhibition and reactive oxygen species elimination by acetyl-CoA acetyltransferase 1 through fused in sarcoma protein to promote prostate cancer. | 1 |
| 36626481 | 2022 | Association between ACAT1 rs1044925 and increased hypertension risk in Tongdao Dong. | 0 |
| 34985712 | 2022 | Epigenetic inactivation of ACAT1 promotes epithelial-mesenchymal transition of clear cell renal cell carcinoma. | 4 |
| 36517760 | 2022 | Autophagy inhibition and reactive oxygen species elimination by acetyl-CoA acetyltransferase 1 through fused in sarcoma protein to promote prostate cancer. | 1 |
| 36626481 | 2022 | Association between ACAT1 rs1044925 and increased hypertension risk in Tongdao Dong. | 0 |
| 33978362 | 2021 | Acyl-Coenzyme A: Cholesterol Acyltransferase-1 is Related to Hyperlipidemia in Children with Nephrotic Syndrome. | 0 |
Citation
Dessen P
ACAT1 (acetyl-CoA acetyltransferase 1)
Atlas Genet Cytogenet Oncol Haematol. 2008-03-01
Online version: http://atlasgeneticsoncology.org/gene/50049/acat1
