Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 57412
MIM: 611806
HGNC: 17452
Ensembl: ENSG00000214435
Variants:
dbSNP: 57412
ClinVar: 57412
TCGA: ENSG00000214435
COSMIC: AS3MT
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000214435 | ENST00000369880 | Q9HBK9 |
| ENSG00000214435 | ENST00000615257 | A0A087WVD4 |
Expression (GTEx)
Pathways
| Pathway | Source | External ID |
|---|---|---|
| Metabolism | REACTOME | R-HSA-1430728 |
| Biological oxidations | REACTOME | R-HSA-211859 |
| Phase II conjugation | REACTOME | R-HSA-156580 |
| Methylation | REACTOME | R-HSA-156581 |
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 35226250 | 2023 | AS3MT facilitates NLRP3 inflammasome activation by m(6)A modification during arsenic-induced hepatic insulin resistance. | 11 |
| 36681142 | 2023 | Arsenic metabolism, N6AMT1 and AS3MT single nucleotide polymorphisms, and their interaction on gestational diabetes mellitus in Chinese pregnant women. | 3 |
| 36940027 | 2023 | As3MT is related to relative RNAs and base modifications of p53 in workers exposed to arsenic. | 1 |
| 37658865 | 2023 | Association between arsenic (+3 oxidation state) methyltransferase gene polymorphisms and arsenic methylation capacity in rural residents of northern China: a cross-sectional study. | 0 |
| 35226250 | 2023 | AS3MT facilitates NLRP3 inflammasome activation by m(6)A modification during arsenic-induced hepatic insulin resistance. | 11 |
| 36681142 | 2023 | Arsenic metabolism, N6AMT1 and AS3MT single nucleotide polymorphisms, and their interaction on gestational diabetes mellitus in Chinese pregnant women. | 3 |
| 36940027 | 2023 | As3MT is related to relative RNAs and base modifications of p53 in workers exposed to arsenic. | 1 |
| 37658865 | 2023 | Association between arsenic (+3 oxidation state) methyltransferase gene polymorphisms and arsenic methylation capacity in rural residents of northern China: a cross-sectional study. | 0 |
| 35719055 | 2022 | Functional characterization of the schizophrenia associated gene AS3MT identifies a role in neuronal development. | 1 |
| 35719055 | 2022 | Functional characterization of the schizophrenia associated gene AS3MT identifies a role in neuronal development. | 1 |
| 32308175 | 2021 | The VNTR of the AS3MT gene is associated with brain activations during a memory span task and their training-induced plasticity. | 8 |
| 32662510 | 2021 | A Human-Specific Schizophrenia Risk Tandem Repeat Affects Alternative Splicing of a Human-Unique Isoform AS3MTd2d3 and Mushroom Dendritic Spine Density. | 13 |
| 33340130 | 2021 | Association between the polymorphism of three genes involved in the methylation and efflux of arsenic (As3MT, MRP1, and P-gp) with lung cancer in a Mexican cohort. | 1 |
| 33649454 | 2021 | Single molecule in situ hybridization reveals distinct localizations of schizophrenia risk-related transcripts SNX19 and AS3MT in human brain. | 3 |
| 32308175 | 2021 | The VNTR of the AS3MT gene is associated with brain activations during a memory span task and their training-induced plasticity. | 8 |
Citation
Dessen P
AS3MT (arsenite methyltransferase)
Atlas Genet Cytogenet Oncol Haematol. 2008-03-01
Online version: http://atlasgeneticsoncology.org/gene/50080/as3mt
