Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 56666
MIM: 608421
HGNC: 8600
Ensembl: ENSG00000073150
Variants:
dbSNP: 56666
ClinVar: 56666
TCGA: ENSG00000073150
COSMIC: PANX2
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000073150 | ENST00000159647 | Q96RD6 |
| ENSG00000073150 | ENST00000395842 | Q96RD6 |
| ENSG00000073150 | ENST00000402472 | F8W8Y4 |
Expression (GTEx)
Pathways
| Pathway | Source | External ID |
|---|---|---|
| Neuronal System | REACTOME | R-HSA-112316 |
| Transmission across Electrical Synapses | REACTOME | R-HSA-112307 |
| Electric Transmission Across Gap Junctions | REACTOME | R-HSA-112303 |
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 36869038 | 2023 | Cryo-EM structure of human heptameric pannexin 2 channel. | 3 |
| 36973289 | 2023 | Structural and functional analysis of human pannexin 2 channel. | 3 |
| 36869038 | 2023 | Cryo-EM structure of human heptameric pannexin 2 channel. | 3 |
| 36973289 | 2023 | Structural and functional analysis of human pannexin 2 channel. | 3 |
| 33913372 | 2021 | PANX2 and brain lower grade glioma genesis: A bioinformatic analysis. | 7 |
| 33913372 | 2021 | PANX2 and brain lower grade glioma genesis: A bioinformatic analysis. | 7 |
| 32770209 | 2020 | Pannexin-2, a novel mitochondrial-associated membrane protein, may become the new strategy to treat and prevent neurological disorders. | 3 |
| 33003647 | 2020 | The Role of miR-342 in Vascular Health. Study in Subclinical Cardiovascular Disease in Mononuclear Cells, Plasma, Inflammatory Cytokines and PANX2. | 15 |
| 32770209 | 2020 | Pannexin-2, a novel mitochondrial-associated membrane protein, may become the new strategy to treat and prevent neurological disorders. | 3 |
| 33003647 | 2020 | The Role of miR-342 in Vascular Health. Study in Subclinical Cardiovascular Disease in Mononuclear Cells, Plasma, Inflammatory Cytokines and PANX2. | 15 |
| 29357945 | 2018 | Human stem cells express pannexins. | 4 |
| 29932112 | 2018 | N-Glycosylation Regulates Pannexin 2 Localization but Is Not Required for Interacting with Pannexin 1. | 9 |
| 29357945 | 2018 | Human stem cells express pannexins. | 4 |
| 29932112 | 2018 | N-Glycosylation Regulates Pannexin 2 Localization but Is Not Required for Interacting with Pannexin 1. | 9 |
| 28036289 | 2017 | Expression of pannexin 1 and 2 in cortical lesions from intractable epilepsy patients with focal cortical dysplasia. | 13 |
Citation
Dessen P
PANX2 (pannexin 2)
Atlas Genet Cytogenet Oncol Haematol. 2008-03-01
Online version: http://atlasgeneticsoncology.org/gene/50085/panx2
