Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 3868
MIM: 148067
HGNC: 6423
Ensembl: ENSG00000186832
Variants:
dbSNP: 3868
ClinVar: 3868
TCGA: ENSG00000186832
COSMIC: KRT16
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000186832 | ENST00000301653 | P08779 |
| ENSG00000186832 | ENST00000590990 | K7ENV3 |
| ENSG00000186832 | ENST00000593067 | K7ENW6 |
Expression (GTEx)
Pathways
| Pathway | Source | External ID |
|---|---|---|
| Developmental Biology | REACTOME | R-HSA-1266738 |
| Keratinization | REACTOME | R-HSA-6805567 |
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38892279 | 2024 | GLI Transcriptional Targets S100A7 and KRT16 Show Upregulated Expression Patterns in Epidermis Overlying the Tumor Mass in Melanoma Samples. | 0 |
| 38892279 | 2024 | GLI Transcriptional Targets S100A7 and KRT16 Show Upregulated Expression Patterns in Epidermis Overlying the Tumor Mass in Melanoma Samples. | 0 |
| 36149327 | 2023 | A novel KRT16 frameshift variant causing pachyonychia congenita by re-initiation of translation. | 0 |
| 37315823 | 2023 | Targeting the KRT16-vimentin axis for metastasis in lung cancer. | 1 |
| 36149327 | 2023 | A novel KRT16 frameshift variant causing pachyonychia congenita by re-initiation of translation. | 0 |
| 37315823 | 2023 | Targeting the KRT16-vimentin axis for metastasis in lung cancer. | 1 |
| 35037835 | 2022 | BarH-like homeobox 2 represses the transcription of keratin 16 and affects Ras signaling pathway to suppress nasopharyngeal carcinoma progression. | 2 |
| 35037835 | 2022 | BarH-like homeobox 2 represses the transcription of keratin 16 and affects Ras signaling pathway to suppress nasopharyngeal carcinoma progression. | 2 |
| 30782177 | 2019 | A novel miR-365-3p/EHF/keratin 16 axis promotes oral squamous cell carcinoma metastasis, cancer stemness and drug resistance via enhancing β5-integrin/c-met signaling pathway. | 49 |
| 30859684 | 2019 | A KRT16 mutation in the first Chinese pedigree with Pachyonychia congenita and review of the literatures. | 2 |
| 30942529 | 2019 | Silencing KRT16 inhibits keratinocyte proliferation and VEGF secretion in psoriasis via inhibition of ERK signaling pathway. | 8 |
| 31337972 | 2019 | TFAP2A Induced KRT16 as an Oncogene in Lung Adenocarcinoma via EMT. | 30 |
| 30782177 | 2019 | A novel miR-365-3p/EHF/keratin 16 axis promotes oral squamous cell carcinoma metastasis, cancer stemness and drug resistance via enhancing β5-integrin/c-met signaling pathway. | 49 |
| 30859684 | 2019 | A KRT16 mutation in the first Chinese pedigree with Pachyonychia congenita and review of the literatures. | 2 |
| 30942529 | 2019 | Silencing KRT16 inhibits keratinocyte proliferation and VEGF secretion in psoriasis via inhibition of ERK signaling pathway. | 8 |
Citation
Dessen P
KRT16 (keratin 16)
Atlas Genet Cytogenet Oncol Haematol. 2008-05-01
Online version: http://atlasgeneticsoncology.org/gene/50129/krt16
