CD163 (CD163 molecule)

2008-05-01  

Identity

HGNC
CD163
LOCATION
12p13.31
LOCUSID
9332
ALIAS
M130,MM130,SCARI1
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 9332
MIM: 605545
HGNC: 1631
Ensembl: ENSG00000177575

Variants:

dbSNP: 9332
ClinVar: 9332
TCGA: ENSG00000177575
COSMIC: CD163

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000177575ENST00000359156Q86VB7
ENSG00000177575ENST00000396620C9JHR8
ENSG00000177575ENST00000432237Q86VB7
ENSG00000177575ENST00000537626H0YFM0
ENSG00000177575ENST00000541972F5GZZ9
ENSG00000177575ENST00000542280H0YGZ7

Expression (GTEx)

0
50
100
150
200
250
300
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
Vesicle-mediated transportREACTOMER-HSA-5653656
Binding and Uptake of Ligands by Scavenger ReceptorsREACTOMER-HSA-2173782
Scavenging of heme from plasmaREACTOMER-HSA-2168880

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
374554602024CD163 as a Potential Biomarker-associated Immune Inflammation in Diabetes Mellitus: A Systematic Review and Bioinformatics Analysis.1
383082982024The relationship between high ratios of CD4/FOXP3 and CD8/CD163 and the improved survivability of metastatic triple-negative breast cancer patients: a multicenter cohort study.0
383739672024Differential expression of Semaphorin-7A /CD163-positive macrophages in large artery and cardiogenic stroke.0
386515472024CD163+ macrophage density in perimysial connective tissue associated with prognosis in IMNM.0
374554602024CD163 as a Potential Biomarker-associated Immune Inflammation in Diabetes Mellitus: A Systematic Review and Bioinformatics Analysis.1
383082982024The relationship between high ratios of CD4/FOXP3 and CD8/CD163 and the improved survivability of metastatic triple-negative breast cancer patients: a multicenter cohort study.0
383739672024Differential expression of Semaphorin-7A /CD163-positive macrophages in large artery and cardiogenic stroke.0
386515472024CD163+ macrophage density in perimysial connective tissue associated with prognosis in IMNM.0
359610242023Urinary CD163 is a marker of active kidney disease in childhood-onset lupus nephritis.5
364690342023Bone marrow expression of CD68/CD163 macrophages, IL-17 and FOXP3 cells in aplastic anemia and their relation to prognosis.2
366177172023Clinical Utility of Soluble CD163 and its Diagnostic and Prognostic Value in a Variety of Neurological Disorders.3
366469522023Prognostic role of the innate immune signature CD163 and "eat me" signal calreticulin in clear cell renal cell carcinoma.0
367400882023The clinical utility of CD163 in viral diseases.2
371653522023Soluble CD163 is a predictor of fibrosis and hepatocellular carcinoma development in nonalcoholic steatohepatitis.0
373010622023Circulating soluble CD163 as a potential biomarker of diabetes complications.0

Citation

Dessen P

CD163 (CD163 molecule)

Atlas Genet Cytogenet Oncol Haematol. 2008-05-01

Online version: http://atlasgeneticsoncology.org/gene/50148/css/tumors-explorer/js/lib/all.min.js