EVL (Enah/Vasp-like)

2008-05-01  

Identity

HGNC
EVL
LOCATION
14q32.2
LOCUSID
51466
ALIAS
RNB6
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 51466
MIM: 616912
HGNC: 20234
Ensembl: ENSG00000196405

Variants:

dbSNP: 51466
ClinVar: 51466
TCGA: ENSG00000196405
COSMIC: EVL

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000196405ENST00000392920Q9UI08
ENSG00000196405ENST00000402714Q9UI08
ENSG00000196405ENST00000402714A0A024R6K5
ENSG00000196405ENST00000544450Q9UI08
ENSG00000196405ENST00000553875G3V535
ENSG00000196405ENST00000554031H0YJL6
ENSG00000196405ENST00000554045G3V3G2
ENSG00000196405ENST00000554695H0YJN0
ENSG00000196405ENST00000555048A0A087WYI2
ENSG00000196405ENST00000555706G3V2K5
ENSG00000196405ENST00000557153G3V5F7
ENSG00000196405ENST00000557384G3V314

Expression (GTEx)

0
10
20
30
40
50
60
70
80
90
100
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
Immune SystemREACTOMER-HSA-168256
Adaptive Immune SystemREACTOMER-HSA-1280218
TCR signalingREACTOMER-HSA-202403
Generation of second messenger moleculesREACTOMER-HSA-202433
Signal TransductionREACTOMER-HSA-162582
Signaling by Rho GTPasesREACTOMER-HSA-194315
RHO GTPase EffectorsREACTOMER-HSA-195258
RHO GTPases Activate ForminsREACTOMER-HSA-5663220
Developmental BiologyREACTOMER-HSA-1266738
Axon guidanceREACTOMER-HSA-422475
Signaling by Robo receptorREACTOMER-HSA-376176

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
372946952023Elevated EVL Methylation Level in the Normal Colon Mucosa Is a Potential Risk Biomarker for Developing Recurrent Adenomas.1
372946952023Elevated EVL Methylation Level in the Normal Colon Mucosa Is a Potential Risk Biomarker for Developing Recurrent Adenomas.1
345508602022Exercise effects on DNA methylation in EVL, CDKN2A (p14, ARF), and ESR1 in colon tissue from healthy men and women.0
345508602022Exercise effects on DNA methylation in EVL, CDKN2A (p14, ARF), and ESR1 in colon tissue from healthy men and women.0
292421012018Epigenetic silencing of EVL/miR-342 in multiple myeloma.12
292421012018Epigenetic silencing of EVL/miR-342 in multiple myeloma.12
286301442017CRMP-1 enhances EVL-mediated actin elongation to build lamellipodia and the actin cortex.12
286301442017CRMP-1 enhances EVL-mediated actin elongation to build lamellipodia and the actin cortex.12
213983692011Biochemical analysis of the human ENA/VASP-family proteins, MENA, VASP and EVL, in homologous recombination.3
213983692011Biochemical analysis of the human ENA/VASP-family proteins, MENA, VASP and EVL, in homologous recombination.3
203796142010Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.78
206395312010Single-stranded DNA catenation mediated by human EVL and a type I topoisomerase.2
203796142010Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.78
206395312010Single-stranded DNA catenation mediated by human EVL and a type I topoisomerase.2
193294392009Recombination activator function of the novel RAD51- and RAD51B-binding protein, human EVL.10

Citation

Dessen P

EVL (Enah/Vasp-like)

Atlas Genet Cytogenet Oncol Haematol. 2008-05-01

Online version: http://atlasgeneticsoncology.org/gene/50152